Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 6/20 | 0.37 |
| ▸ | NOS1 | P29475 | 4/20 | 0.37 |
| ▸ | NOS3 | P29474 | 3/20 | 0.37 |
| ▸ | ARG1 | P05089 | 1/20 | 0.33 |
| ▸ | ARG2 | P78540 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9809057 | 0.98 | NOS2 (0.36) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL1262927 | 0.84 | — | — | |
| SCHEMBL8022124 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL11129922 | 0.81 | — | — | |
| SCHEMBL8022170 | 0.77 | — | — | |
| SCHEMBL11114575 | 0.77 | — | — | |
| SCHEMBL9809030 | 0.76 | METAP2 (0.37) | CYP2C19 | |
| Hydrochloric Acid SCHEMBL11113277 | 0.76 | NOS2 (0.38) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL21955443 | 0.75 | ARG1 (0.36) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL8024940 | 0.74 | NOS2 (0.44) | NOS2NOS1NOS3ARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322633-B1 | MERCAPTO-ACYLAMINO ACID ANTIHYPERTENSIVES | SCHERING CORPORATION (US) | 1991-05-22 | — | — | EP | disclosed |
| EP-0390839-A1 | MERCAPTO-ACYLAMINO ACID ANTIHYPERTENSIVES | SCHERING CORPORATION (US) | 1990-10-10 | — | — | EP | disclosed |
| WO-1989005796-A1 | MERCAPTO-ACYLAMINO ACID ANTIHYPERTENSIVES | SCHERING CORPORATION (US) | 1989-06-29 | — | — | WO | disclosed |