Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9809070 | 0.84 | KMT2A (0.50) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL9809074 | 0.82 | KMT2A (0.47) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL9809067 | 0.80 | CYP19A1 (0.42) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL9809114 | 0.72 | CYP19A1 (0.43) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL9809061 | 0.68 | MGLL (0.37) | ALDH1A1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL3882745 | 0.66 | CYP19A1 (0.56) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL536896 | 0.65 | CYP19A1 (0.55) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL9809118 | 0.62 | POLB (0.42) | ALDH1A1KMT2AMEN1LMNATSHR | |
| SCHEMBL15268809 | 0.61 | ALDH1A1 (0.49) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL9809062 | 0.61 | CYP19A1 (0.38) | ALDH1A1KMT2AMEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063245-A | Hormone inhibitors | NOVA PHARMACEUTICAL CORPORATION (US) | 1991-11-05 | — | — | US | disclosed |