Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9809070 | 0.88 | KMT2A (0.50) | KMT2AMEN1ALDH1A1LMNAKDM4E | |
| SCHEMBL9809076 | 0.82 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1LMNAKDM4E | |
| SCHEMBL9809121 | 0.78 | POLB (0.40) | KMT2AMEN1ALDH1A1LMNANPSR1 | |
| SCHEMBL9809118 | 0.65 | POLB (0.42) | KMT2AMEN1ALDH1A1LMNANPSR1 | |
| SCHEMBL15268809 | 0.64 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1LMNAKDM4E | |
| SCHEMBL17264297 | 0.63 | BCHE (0.54) | KMT2AMEN1ALDH1A1LMNAKDM4E | |
| SCHEMBL7828945 | 0.63 | LMNA (0.49) | KMT2AMEN1ALDH1A1LMNAKDM4E | |
| SCHEMBL9809069 | 0.63 | ALOX15 (0.58) | KMT2AMEN1ALDH1A1LMNAKDM4E | |
| SCHEMBL7821723 | 0.62 | LMNA (0.50) | ALDH1A1LMNAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL13562506 | 0.61 | MEN1 (0.55) | KMT2AMEN1ALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063245-A | Hormone inhibitors | NOVA PHARMACEUTICAL CORPORATION (US) | 1991-11-05 | — | — | US | disclosed |