Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 3/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 5/20 | 0.32 |
| ▸ | CA2 | P00918 | 5/20 | 0.32 |
| ▸ | CA7 | P43166 | 4/20 | 0.32 |
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA6 | P23280 | 2/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | NT5E | P21589 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL10981400 | 0.92 | CA1 (0.36) | CA5ACA5BBLMLMNASLC6A6 | |
| SCHEMBL9809081 | 0.85 | CA2 (0.33) | CA1CA2CA7CA12CA9 | |
| SCHEMBL545418 | 0.82 | LOXL2 (0.33) | — | |
| Hydrochloric Acid SCHEMBL3673293 | 0.78 | LOXL2 (0.32) | — | |
| SCHEMBL554229 | 0.78 | SLC6A2 (0.33) | — | |
| Sulfuric Acid SCHEMBL7708289 | 0.71 | CA5A (0.55) | CA5ACA5BBLMCA1CA2 | |
| SCHEMBL16182175 | 0.69 | — | — | |
| SCHEMBL1809934 | 0.69 | — | — | |
| Sulfuric Acid SCHEMBL11277179 | 0.67 | — | — | |
| Sulfuric Acid SCHEMBL28084309 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117020-B1 | METHOD OF PREPARING TETRAHALOBENZENE COMPOUNDS, CHEMICAL INTERMEDIATES USED THEREIN AND CERTAIN OF THE COMPOUNDS THEMSELVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-05-22 | — | — | EP | disclosed |
| US-4550206-A | Method of preparing tetrahalobenzene compounds, chemical intermediates used therein and certain of the compounds themselves | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1985-10-29 | — | — | US | disclosed |
| US-4492617-A | Method of preparing tetrahalobenzene compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-01-08 | — | — | US | disclosed |
| EP-0117020-A2 | Method of preparing tetrahalobenzene compounds, chemical intermediates used therein and certain of the compounds themselves | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-08-29 | — | — | EP | disclosed |