Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 16/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9809088 | 0.71 | FPR2 (0.47) | NR1I2LMNACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9809104 | 0.68 | TSHR (0.34) | NR1I2LMNACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL682819 | 0.67 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| SCHEMBL659743 | 0.67 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| SCHEMBL1552999 | 0.67 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| SCHEMBL16416157 | 0.66 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| Methane SCHEMBL27798790 | 0.66 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| Hydrochloric Acid SCHEMBL4772964 | 0.66 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| SCHEMBL28253269 | 0.65 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| SCHEMBL9809065 | 0.64 | ALOX15 (0.62) | LMNACYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063245-A | Hormone inhibitors | NOVA PHARMACEUTICAL CORPORATION (US) | 1991-11-05 | — | — | US | disclosed |