Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9809094 | 0.73 | FPR2 (0.45) | TSHRLMNANR1I2CYP3A4CYP2D6 | |
| SCHEMBL9809109 | 0.68 | SLC6A2 (0.44) | TSHRLMNANR1I2CYP3A4CYP2D6 | |
| SCHEMBL9809069 | 0.66 | ALOX15 (0.58) | TSHRLMNACYP2D6PTGS2ALOX15 | |
| SCHEMBL5408210 | 0.66 | POLB (0.54) | OPRM1OPRK1OGFRL1OPRD1OPRL1 | |
| SCHEMBL1176855 | 0.66 | POLB (0.54) | OPRM1OPRK1OGFRL1OPRD1OPRL1 | |
| SCHEMBL2333756 | 0.66 | POLB (0.54) | OPRM1OPRK1OGFRL1OPRD1OPRL1 | |
| Hydrochloric Acid SCHEMBL17700584 | 0.64 | POLB (0.53) | OPRM1OPRK1OGFRL1OPRD1OPRL1 | |
| SCHEMBL9809088 | 0.62 | FPR2 (0.47) | TSHRLMNANR1I2CYP3A4CYP2D6 | |
| SCHEMBL944734 | 0.60 | GPR84 (0.48) | TSHRLMNAOPRM1OPRK1OGFRL1 | |
| SCHEMBL1176600 | 0.60 | CRBN (0.37) | OPRM1OPRK1OGFRL1OPRD1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063245-A | Hormone inhibitors | NOVA PHARMACEUTICAL CORPORATION (US) | 1991-11-05 | — | — | US | disclosed |