Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | F13A1 | P00488 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654494 | 0.83 | KMT2A (0.45) | ALDH1A1PKMKMT2AMEN1GAA | |
| SCHEMBL7619544 | 0.80 | KMT2A (0.43) | ALDH1A1KMT2AMEN1LMNAGAA | |
| SCHEMBL9185188 | 0.79 | CARM1 (0.41) | ALDH1A1KMT2AMEN1GAARXFP1 | |
| SCHEMBL32664495 | 0.78 | CA12 (0.61) | ALDH1A1PKMTDP1L3MBTL1POLB | |
| SCHEMBL6411427 | 0.78 | KMT2A (0.42) | ALDH1A1KMT2AMEN1LMNAGAA | |
| SCHEMBL634315 | 0.78 | CA12 (0.61) | ALDH1A1PKMTDP1L3MBTL1POLB | |
| SCHEMBL9307534 | 0.78 | MAPK1 (0.65) | ALDH1A1PKMLMNATSHRTDP1 | |
| SCHEMBL1395581 | 0.78 | ALDH1A1 (0.50) | ALDH1A1PKMKMT2AMEN1TDP1 | |
| SCHEMBL8851837 | 0.77 | PKM (0.52) | ALDH1A1PKMKMT2ALMNATDP1 | |
| SCHEMBL3620171 | 0.77 | KMT2A (0.41) | ALDH1A1KMT2AMEN1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983744-A | Substituted thienylethylamines and process for their production | LONZA LTD. (CH) | 1991-01-08 | — | — | US | disclosed |
| US-4970325-A | Substituted thienylethylamines and process for their production | LONZA LTD. (CH) | 1990-11-13 | — | — | US | disclosed |