SCHEMBL9809595

SCHEMBL9809595

O=C(Oc1ccccc1)Oc1ccc2c(=O)c3ccc(OC(=O)Oc4ccccc4)cc3oc2c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.72
MAPT P10636 7/20 0.72
ALDH1A1 P00352 6/20 0.72
PPARG P37231 1/20 0.72
NCOA2 Q15596 1/20 0.72
NPSR1 Q6W5P4 1/20 0.72
RXFP1 Q9HBX9 1/20 0.72
NPC1 O15118 4/20 0.55
RAB9A P51151 4/20 0.55
MAOA P21397 2/20 0.55
KDM4E B2RXH2 5/20 0.53
TTR P02766 1/20 0.51
MEN1 O00255 5/20 0.51
HPGD P15428 3/20 0.51
TP53 P04637 3/20 0.51
HSD17B10 Q99714 3/20 0.51
CYP2C9 P11712 1/20 0.51
PTGER1 P34995 1/20 0.51
PTGER3 P43115 1/20 0.51
PTGER2 P43116 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9809610 0.83 KDM4E (0.56) KMT2AMAPTALDH1A1PPARGNCOA2
SCHEMBL8662334 0.80 TTR (0.61) KMT2AMAPTALDH1A1PPARGNCOA2
SCHEMBL7328681 0.79 NPC1 (0.68) KMT2AMAPTALDH1A1PPARGNCOA2
SCHEMBL20317223 0.77 KDM4E (0.62) KMT2AMAPTALDH1A1NPC1RAB9A
SCHEMBL10611335 0.76 NPC1 (0.82) KMT2AMAPTALDH1A1NPC1RAB9A
SCHEMBL1624304 0.75 KMT2A (0.52) KMT2AMAPTALDH1A1PPARGNCOA2
SCHEMBL9413588 0.74 NPC1 (0.68) KMT2AMAPTALDH1A1NPC1RAB9A
SCHEMBL9837487 0.74 LMNA (0.72) KMT2AMAPTALDH1A1NPC1RAB9A
SCHEMBL25490125 0.74 MAPT (0.63) KMT2AMAPTALDH1A1PPARGNCOA2
SCHEMBL8961859 0.73 ALDH1A1 (0.72) KMT2AMAPTALDH1A1NPSR1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0198798-B1 LIGHT-SENSITIVE POLYCONDENSATES, PROCESS FOR THEIR PREPARATION, MATERIALS COATED THEREWITH AND THEIR USE CIBA-GEIGY AG (CH) 1991-05-29 EP disclosed
EP-0198798-A2 Light-sensitive polycondensates, process for their preparation, materials coated therewith and their use CIBA-GEIGY AG (CH) 1986-10-22 EP disclosed