Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 10/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.56 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.56 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9809657 | 0.83 | OPRM1 (0.61) | APPSIGMAR1TMEM97OPRK1 | |
| SCHEMBL9809660 | 0.79 | OPRM1 (0.54) | APPSIGMAR1TMEM97OPRK1 | |
| SCHEMBL9809664 | 0.79 | MAPT (0.54) | APPSIGMAR1TMEM97OPRK1 | |
| SCHEMBL9809684 | 0.79 | MAPT (0.54) | APPSIGMAR1TMEM97OPRK1 | |
| SCHEMBL9809676 | 0.79 | OPRM1 (0.58) | APPSIGMAR1TMEM97OPRK1 | |
| SCHEMBL9809729 | 0.79 | ALDH1A1 (0.61) | APPSIGMAR1TMEM97OPRK1 | |
| SCHEMBL9809635 | 0.79 | GAA (0.53) | APPSIGMAR1TMEM97OPRK1 | |
| SCHEMBL9809681 | 0.77 | OPRM1 (0.56) | APPSIGMAR1TMEM97OPRK1 | |
| SCHEMBL28844172 | 0.76 | SIGMAR1 (0.67) | APPSIGMAR1TMEM97OPRK1 | |
| SCHEMBL8980565 | 0.74 | KDM4E (0.56) | APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071850-A | Cardiovascular disorders | PIERRE FABRE MEDICAMENT (FR) | 1991-12-10 | — | — | US | disclosed |