Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 6/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10088928 | 0.85 | PDE3B (0.38) | PTGS1PTGS2NR3C2KDM4EESR1 | |
| SCHEMBL10088484 | 0.81 | NR3C2 (0.53) | PTGS1PTGS2NR3C2 | |
| SCHEMBL2324684 | 0.80 | TYR (0.41) | PTGS1PTGS2KDM4EPOLBESR1 | |
| SCHEMBL31544361 | 0.76 | ALOX5 (0.54) | PTGS1PTGS2ALOX5KDM4ETDP1 | |
| SCHEMBL10088934 | 0.76 | RARA (0.38) | PTGS1PTGS2ALOX5KDM4EPOLB | |
| SCHEMBL9729530 | 0.76 | ALOX5 (0.54) | PTGS1PTGS2ALOX5KDM4ETDP1 | |
| SCHEMBL10088907 | 0.76 | ALOX5 (0.40) | PTGS1PTGS2ALOX5KDM4EPOLB | |
| SCHEMBL31265526 | 0.76 | ALDH1A1 (0.43) | PTGS1PTGS2KDM4EPOLBTDP1 | |
| SCHEMBL29804937 | 0.75 | PTGS1 (0.51) | PTGS1PTGS2ALOX5KDM4EPOLB | |
| SCHEMBL2568148 | 0.75 | PTGS1 (0.51) | PTGS1PTGS2ALOX5KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5004744-A | Durability; effectiveness at low concentration | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-02 | — | — | US | disclosed |