SCHEMBL9810260

SCHEMBL9810260

CCCCCCC(C)OC(=O)C1CC=C(C2=CCC(c3ccc(OC)cc3)CC2)CC1

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
MMP9 P14780 4/20 0.35
MMP13 P45452 4/20 0.35
ADAM17 P78536 4/20 0.35
MMP1 P03956 4/20 0.35
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
MMP2 P08253 1/20 0.34
MMP3 P08254 1/20 0.34
PNLIP P16233 1/20 0.34
NAAA Q02083 1/20 0.33
DRD2 P14416 1/20 0.33
USP30 Q70CQ3 2/20 0.32
KDM4E B2RXH2 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9810421 0.84 PPARG (0.37) ALDH1A1KMT2AMEN1DRD2
SCHEMBL9810401 0.84 PPARG (0.37) ALDH1A1KMT2AMEN1DRD2
SCHEMBL9810350 0.84 SLC6A2 (0.43) ALDH1A1KMT2AMEN1
SCHEMBL9810392 0.83 ALDH1A1 (0.37) ALDH1A1KMT2AMEN1DRD2
SCHEMBL9810475 0.83 ALDH1A1 (0.39) ALDH1A1KMT2AMEN1DRD2
SCHEMBL9810635 0.83 DRD2 (0.34) ALDH1A1KMT2AMEN1DRD2
SCHEMBL9810293 0.80 DRD2 (0.38) ALDH1A1KMT2AMEN1DRD2KDM4E
SCHEMBL9810622 0.80 GAA (0.43) ALDH1A1KMT2AMEN1KDM4E
SCHEMBL9810403 0.79 PKM (0.41) ALDH1A1KMT2AMEN1NAAAL3MBTL1
SCHEMBL9810562 0.72 RARB (0.42) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5068389-A TERTIARY ALCOHOLS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-11-26 US disclosed