Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.35 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.35 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9810392 | 0.98 | ALDH1A1 (0.37) | ALDH1A1KMT2AMEN1RAB9ADRD2 | |
| SCHEMBL9810401 | 0.97 | PPARG (0.37) | ALDH1A1KMT2AMEN1RAB9ADRD2 | |
| SCHEMBL9810421 | 0.97 | PPARG (0.37) | ALDH1A1KMT2AMEN1RAB9ADRD2 | |
| SCHEMBL9810293 | 0.94 | DRD2 (0.38) | ALDH1A1KMT2AMEN1RAB9ADRD2 | |
| SCHEMBL9810622 | 0.90 | GAA (0.43) | ALDH1A1KMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL9810403 | 0.85 | PKM (0.41) | ALDH1A1KMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL9810635 | 0.85 | DRD2 (0.34) | ALDH1A1KMT2AMEN1RAB9ADRD2 | |
| SCHEMBL9810260 | 0.83 | ALDH1A1 (0.35) | ALDH1A1KMT2AMEN1DRD2 | |
| SCHEMBL9810350 | 0.81 | SLC6A2 (0.43) | ALDH1A1KMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL9810695 | 0.80 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1RAB9ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068389-A | TERTIARY ALCOHOLS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |