Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9810335 | 1.00 | PPARG (0.42) | PPARGLMNATSHRALDH1A1L3MBTL1 | |
| SCHEMBL9810345 | 1.00 | PPARG (0.42) | PPARGLMNATSHRALDH1A1L3MBTL1 | |
| SCHEMBL9810267 | 0.99 | LMNA (0.40) | PPARGLMNATSHRALDH1A1L3MBTL1 | |
| SCHEMBL9810508 | 0.95 | L3MBTL1 (0.41) | PPARGLMNATSHRALDH1A1L3MBTL1 | |
| SCHEMBL9810279 | 0.92 | OPRL1 (0.43) | PPARGS1PR5S1PR1S1PR3 | |
| SCHEMBL9810336 | 0.92 | THRA (0.43) | PPARGS1PR5S1PR1S1PR3 | |
| SCHEMBL9810387 | 0.92 | THRA (0.43) | PPARGS1PR5S1PR1S1PR3 | |
| SCHEMBL9810321 | 0.92 | PPARG (0.41) | PPARGLMNATSHRALDH1A1S1PR5 | |
| SCHEMBL9810485 | 0.92 | THRA (0.43) | PPARGS1PR5S1PR1S1PR3 | |
| SCHEMBL9810477 | 0.92 | THRA (0.43) | PPARGS1PR5S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068389-A | TERTIARY ALCOHOLS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |