Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9810267 | 0.96 | LMNA (0.40) | L3MBTL1LMNANPC1TSHROPRL1 | |
| SCHEMBL9810345 | 0.95 | PPARG (0.42) | L3MBTL1LMNANPC1TSHRMAPK1 | |
| SCHEMBL9810335 | 0.95 | PPARG (0.42) | L3MBTL1LMNANPC1TSHRMAPK1 | |
| SCHEMBL9810450 | 0.95 | PPARG (0.42) | L3MBTL1LMNANPC1TSHRMAPK1 | |
| SCHEMBL9810568 | 0.92 | LMNA (0.43) | L3MBTL1LMNANPC1OPRL1OPRM1 | |
| SCHEMBL9810420 | 0.91 | OPRL1 (0.45) | OPRL1OPRM1OPRD1OPRK1MEN1 | |
| SCHEMBL9810669 | 0.91 | OPRL1 (0.41) | OPRL1OPRM1OPRD1OPRK1MEN1 | |
| SCHEMBL9810385 | 0.90 | THRB (0.42) | OPRL1ALDH1A1 | |
| SCHEMBL9810307 | 0.89 | THRB (0.43) | OPRL1 | |
| SCHEMBL9810482 | 0.89 | THRB (0.43) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068389-A | TERTIARY ALCOHOLS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |