Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9810674 | 0.96 | THRA (0.54) | THRATHRBOPRL1SLC6A3S1PR1 | |
| SCHEMBL9810418 | 0.95 | THRA (0.55) | THRATHRBOPRL1S1PR1 | |
| SCHEMBL9810306 | 0.95 | THRA (0.55) | THRATHRBOPRL1S1PR1 | |
| SCHEMBL9810264 | 0.95 | THRA (0.55) | THRATHRBOPRL1S1PR1 | |
| SCHEMBL9810262 | 0.92 | OPRL1 (0.44) | THRATHRBOPRL1SLC6A3PLK1 | |
| SCHEMBL9810458 | 0.89 | OPRL1 (0.46) | OPRL1ALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL9810349 | 0.88 | OPRL1 (0.45) | THRATHRBOPRL1SLC6A3PLK1 | |
| SCHEMBL9810420 | 0.88 | OPRL1 (0.45) | THRATHRBOPRL1PLK1ALDH1A1 | |
| SCHEMBL9810441 | 0.87 | ALDH1A1 (0.46) | OPRL1SLC6A3ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9810615 | 0.86 | OPRL1 (0.44) | THRATHRBOPRL1S1PR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068389-A | TERTIARY ALCOHOLS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |