Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9810262 | 0.89 | OPRL1 (0.44) | ALDH1A1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL9810410 | 0.87 | LMNA (0.53) | ALDH1A1NPSR1OPRM1OPRD1OPRK1 | |
| SCHEMBL9810484 | 0.87 | THRA (0.49) | ALDH1A1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL9810674 | 0.85 | THRA (0.54) | ALDH1A1OPRL1SLC6A3 | |
| SCHEMBL9810568 | 0.85 | LMNA (0.43) | ALDH1A1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL9810264 | 0.84 | THRA (0.55) | OPRL1 | |
| SCHEMBL9810306 | 0.84 | THRA (0.55) | OPRL1 | |
| SCHEMBL9810418 | 0.84 | THRA (0.55) | OPRL1 | |
| SCHEMBL9810256 | 0.84 | ALDH1A1 (0.48) | ALDH1A1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL9797993 | 0.84 | ALDH1A1 (0.49) | ALDH1A1OPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068389-A | TERTIARY ALCOHOLS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |