Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 2/20 | 0.57 |
| ▸ | HSPA8 | P11142 | 2/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.43 |
| ▸ | ADA | P00813 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAPDH | P04406 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29709122 | 0.88 | ADORA2A (0.56) | HSPA5HSPA8RXFP1ADORA3ADORA2A | |
| SCHEMBL9617721 | 0.88 | HSPA5 (0.46) | HSPA5HSPA8RXFP1ADORA3ADORA2A | |
| SCHEMBL19680287 | 0.88 | AHCY (0.54) | HSPA5HSPA8RXFP1ADORA3ADORA2A | |
| SCHEMBL29328691 | 0.88 | ADORA2A (0.56) | HSPA5HSPA8RXFP1ADORA3ADORA2A | |
| SCHEMBL23679560 | 0.85 | HSPA8 (0.45) | HSPA5HSPA8RXFP1ADORA3ADORA2A | |
| SCHEMBL9810713 | 0.85 | HSPA8 (0.45) | HSPA5HSPA8RXFP1ADORA3ADORA2A | |
| SCHEMBL10381269 | 0.79 | ADA (0.65) | ADORA3ADORA2AADORA1ADORA2BADA | |
| SCHEMBL8094890 | 0.79 | ADA (0.65) | ADORA3ADORA2AADORA1ADORA2BADA | |
| SCHEMBL3541 | 0.79 | ADA (0.65) | ADORA3ADORA2AADORA1ADORA2BADA | |
| SCHEMBL9197787 | 0.79 | ADA (0.65) | ADORA3ADORA2AADORA1ADORA2BADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5013829-A | Stable congener of 2',3'-dideoxyadenosine | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1991-05-07 | — | — | US | disclosed |