Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304684 | 0.77 | POLB (0.53) | POLBMAPK1L3MBTL1PPARAHPGD | |
| SCHEMBL10645293 | 0.75 | L3MBTL1 (0.53) | POLBMAPK1L3MBTL1HPGDALDH1A1 | |
| SCHEMBL22606841 | 0.75 | MAPK1 (0.56) | POLBMAPK1L3MBTL1HPGDALDH1A1 | |
| SCHEMBL10757211 | 0.74 | MAPK1 (0.51) | POLBMAPK1L3MBTL1PPARGPPARA | |
| SCHEMBL10764127 | 0.72 | POLB (0.52) | POLBMAPK1L3MBTL1HPGDALDH1A1 | |
| SCHEMBL9306312 | 0.71 | POLB (0.56) | POLBMAPK1L3MBTL1PPARAHPGD | |
| SCHEMBL14156242 | 0.71 | POLB (0.50) | POLBMAPK1L3MBTL1PPARAHPGD | |
| SCHEMBL11114226 | 0.71 | POLB (0.55) | POLBMAPK1HPGDALDH1A1MAPT | |
| SCHEMBL11352115 | 0.70 | POLB (0.55) | POLBMAPK1L3MBTL1PPARAHPGD | |
| SCHEMBL9256223 | 0.70 | ALDH1A1 (0.56) | POLBMAPK1L3MBTL1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161219-B1 | HETEROCYCLIC MERCAPTOCARBOXYLIC-ACID ESTERS AND ANHYDRIDES AS CORROSION INHIBITING AGENTS | CIBA-GEIGY AG (CH) | 1991-06-12 | — | — | EP | disclosed |
| EP-0161219-A2 | Heterocyclic mercaptocarboxylic-acid esters and anhydrides as corrosion inhibiting agents | CIBA-GEIGY AG (CH) | 1985-11-13 | — | — | EP | disclosed |