Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6119974 | 0.79 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2CES2CES1LMNA | |
| SCHEMBL9811397 | 0.76 | CES1 (0.48) | ALDH1A1SMN1; SMN2CES2CES1LMNA | |
| SCHEMBL5641416 | 0.73 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2CES2CES1LMNA | |
| P-Xylene SCHEMBL28670186 | 0.72 | ACHE (0.57) | ALDH1A1SMN1; SMN2CES2CES1LMNA | |
| SCHEMBL9703890 | 0.71 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2CES2CES1LMNA | |
| P-Xylene SCHEMBL28442305 | 0.71 | ACHE (0.80) | ALDH1A1SMN1; SMN2CES2CES1LMNA | |
| P-Xylene SCHEMBL28696945 | 0.71 | ACHE (0.80) | ALDH1A1SMN1; SMN2CES2CES1LMNA | |
| 4-Methylbenzoic Acid SCHEMBL93638 | 0.70 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2CES2CES1LMNA | |
| Terephthalic Acid SCHEMBL15994097 | 0.70 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2CES2CES1LMNA | |
| Terephthalic Acid SCHEMBL526449 | 0.70 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2CES2CES1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431122-A1 | RADIATION-CURABLE BINDING AGENT SYSTEMS WITH ALPHA-SUBSTITUTED SULPHONYL COMPOUNDS AS PHOTO-ACTIVATORS | CIBA-GEIGY AG (CH) | 1991-06-12 | — | — | EP | disclosed |
| WO-1991000312-A1 | RADIATION-CURABLE BINDING AGENT SYSTEMS WITH ALPHA-SUBSTITUTED SULPHONYL COMPOUNDS AS PHOTO-ACTIVATORS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-01-10 | — | — | WO | disclosed |