Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 2/20 | 0.34 |
| ▸ | CELA1 | Q9UNI1 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9811685 | 0.84 | AKR1B1 (0.39) | TDP1MEN1KMT2ARAB9AGABRA1 | |
| SCHEMBL9797363 | 0.79 | TSHR (0.46) | TDP1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL9811748 | 0.79 | ALDH1A1 (0.36) | TDP1ALDH1A1NPSR1GABRA1GABRB1 | |
| SCHEMBL4645395 | 0.78 | ABCB11 (0.49) | TDP1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL9811683 | 0.76 | GAA (0.46) | TDP1ALDH1A1NPSR1 | |
| SCHEMBL9797399 | 0.75 | GABRA1 (0.50) | MEN1KMT2AALDH1A1NPSR1GABRA1 | |
| SCHEMBL18871612 | 0.73 | ABCB11 (0.45) | TDP1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL3400325 | 0.73 | GABRA1 (0.61) | TDP1MEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL11245676 | 0.72 | ABCB11 (0.41) | TDP1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL9797748 | 0.72 | GABRA1 (0.36) | ALDH1A1GABRA1GABRB1ELANELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5064861-A | ACYLATED AMINE COMPOUNDS WHICH ARE USEFUL FUNGICIGAL AGENTS | ROUSSEL UCLAF (FR) | 1991-11-12 | — | — | US | disclosed |