Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.54 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9811885 | 0.89 | ADRB2 (0.53) | ADRB2ADRB1ADRB3L3MBTL1LTA4H | |
| SCHEMBL9811884 | 0.87 | ADRB2 (0.54) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9812082 | 0.85 | SIGMAR1 (0.57) | ADRB2ADRB1ADRB3GLAMEN1 | |
| Hydrochloric Acid SCHEMBL9812083 | 0.81 | SLC2A1 (0.60) | ADRB2ADRB1ADRB3GLAMEN1 | |
| SCHEMBL8880483 | 0.81 | GLA (0.55) | ADRB2ADRB1ADRB3GLAMEN1 | |
| SCHEMBL11247530 | 0.81 | ADRB3 (0.77) | ADRB2ADRB1ADRB3GLAADRA1D | |
| SCHEMBL11251142 | 0.81 | ADRB3 (0.77) | ADRB2ADRB1ADRB3GLAADRA1D | |
| SCHEMBL9812030 | 0.80 | SMN1; SMN2 (0.50) | ADRB2ADRB1ADRB3LTA4HMAPT | |
| SCHEMBL9811917 | 0.80 | SIGMAR1 (0.54) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL9684241 | 0.80 | ADRB1 (0.65) | ADRB2ADRB1ADRB3GLAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0170121-B1 | 2-HYDROXY-3-ARYLOXYPROPYL OR 2-HYDROXY-2-BENZOFURANYL ETHYL TERTIARY AMINE HAVING AN ANTI-HYPERGLYCAEMIC AND/OR ANTI-OBESITY ACTIVITY | BEECHAM GROUP PLC (GB) | 1991-06-19 | — | — | EP | disclosed |
| EP-0170121-A1 | 2-Hydroxy-3-aryloxypropyl or 2-hydroxy-2-benzofuranyl ethyl tertiary amine having an anti-hyperglycaemic and/or anti-obesity activity | BEECHAM GROUP PLC (GB) | 1986-02-05 | — | — | EP | disclosed |