SCHEMBL9812562

SCHEMBL9812562

O=C(OCc1ccccc1Cl)C(F)(F)F

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.50
CASP3 P42574 3/20 0.49
SENP8 Q96LD8 3/20 0.49
SENP7 Q9BQF6 3/20 0.49
SENP6 Q9GZR1 3/20 0.49
MMP1 P03956 1/20 0.49
MMP2 P08253 1/20 0.49
MMP9 P14780 1/20 0.49
MMP12 P39900 1/20 0.49
MAOA P21397 1/20 0.49
MAOB P27338 1/20 0.49
IDO1 P14902 2/20 0.47
RAB9A P51151 4/20 0.47
MAPT P10636 2/20 0.47
NR4A2 P43354 2/20 0.46
POLB P06746 1/20 0.46
NPC1 O15118 3/20 0.45
ALDH1A1 P00352 2/20 0.44
HPGD P15428 1/20 0.44
HTT P42858 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24901041 0.85 L3MBTL1 (0.47) L3MBTL1CASP3SENP8SENP7SENP6
SCHEMBL12330408 0.83 MAOA (0.53) L3MBTL1CASP3SENP8SENP7SENP6
SCHEMBL28245986 0.81 MAOA (0.51) L3MBTL1CASP3SENP8SENP7SENP6
SCHEMBL28109969 0.81 IDO1 (0.48) IDO1RAB9AMAPTHTTKMT2A
SCHEMBL984297 0.80 L3MBTL1 (0.57) L3MBTL1CASP3SENP8SENP7SENP6
SCHEMBL9815841 0.80 L3MBTL1 (0.57) L3MBTL1CASP3SENP8SENP7SENP6
SCHEMBL9812396 0.79 MMP1 (0.49) L3MBTL1MMP1MMP2MMP9MMP12
SCHEMBL5439590 0.79 IDO1 (0.47) MMP1MMP2MMP9MMP12MAOA
SCHEMBL11581518 0.78 L3MBTL1 (0.55) L3MBTL1CASP3SENP8SENP7SENP6
SCHEMBL140814 0.78 ALDH1A1 (0.57) L3MBTL1CASP3SENP8SENP7SENP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0451201-A1 PREPARATION OF BIDENTATE LIGANDS EASTMAN KODAK COMPANY (US) 1991-10-16 EP claimed
WO-1990006930-A1 PREPARATION OF BIDENTATE LIGANDS EASTMAN KODAK COMPANY (US) 1990-06-28 WO claimed
EP-0375576-A1 Preparation of bidentate ligands EASTMAN KODAK COMPANY (US) 1990-06-27 EP claimed
CN-116751118-B Preparation method of chiral alpha-alkyl-alpha-benzyl tetralone compound 苏州凯若利新材料科技有限公司 2025-05-30 CN disclosed
CN-116751118-A Preparation method of chiral alpha-alkyl-alpha-benzyl tetralone compound 苏州凯若利新材料科技有限公司 2023-09-15 CN disclosed
EP-0451201-A1 PREPARATION OF BIDENTATE LIGANDS EASTMAN KODAK COMPANY (US) 1991-10-16 EP disclosed
WO-1990006930-A1 PREPARATION OF BIDENTATE LIGANDS EASTMAN KODAK COMPANY (US) 1990-06-28 WO disclosed
EP-0375576-A1 Preparation of bidentate ligands EASTMAN KODAK COMPANY (US) 1990-06-27 EP disclosed