Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.67 |
| ▸ | CA12 | O43570 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA4 | P22748 | 3/20 | 0.52 |
| ▸ | CA9 | Q16790 | 3/20 | 0.52 |
| ▸ | NAMPT | P43490 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP14 | P50281 | 1/20 | 0.48 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9659360 | 0.89 | TBXA2R (0.58) | CYP19A1CA12CA1CA2CA4 | |
| SCHEMBL9661159 | 0.87 | CYP19A1 (0.65) | CYP19A1CA12CA1CA2CA4 | |
| SCHEMBL9813027 | 0.87 | TBXAS1 (0.51) | CYP19A1CA12CA1CA2CA4 | |
| SCHEMBL9812978 | 0.87 | TBXA2R (0.60) | CYP19A1CA12CA1CA2CA4 | |
| SCHEMBL7327586 | 0.82 | EPHX2 (0.58) | LMNAARMEN1KMT2A | |
| SCHEMBL9813032 | 0.80 | CTSL (0.46) | CYP19A1CA12CA1CA2CA4 | |
| SCHEMBL9813030 | 0.80 | CTSL (0.46) | CYP19A1CA12CA1CA2CA4 | |
| SCHEMBL9129363 | 0.80 | TBXA2R (0.57) | CA12CA1CA2CA4CA9 | |
| SCHEMBL9813031 | 0.78 | CYP19A1 (0.82) | CYP19A1CA1CA2NAMPTLMNA | |
| SCHEMBL1753546 | 0.78 | PTGDR2 (0.67) | CYP19A1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223593-B1 | PHENOXYALKYLCARBOXYLIC ACIDS AND ESTERS AND THEIR PREPARATION AND PHARMACEUTICAL FORMULATION | GLAXO GROUP LIMITED (GB) | 1991-08-07 | — | — | EP | disclosed |
| EP-0223593-A2 | Phenoxyalkylcarboxylic acids and esters and their preparation and pharmaceutical formulation | GLAXO GROUP LIMITED (GB) | 1987-05-27 | — | — | EP | disclosed |