Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 1/20 | 0.60 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.60 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA4 | P22748 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9661159 | 0.90 | CYP19A1 (0.65) | TBXA2RTBXAS1FFAR1CA12CA1 | |
| SCHEMBL9813017 | 0.87 | TBXA2R (0.75) | TBXA2RTBXAS1MAPTHDAC2HDAC8 | |
| SCHEMBL9812957 | 0.87 | CYP19A1 (0.67) | CA12CA1CA2CA4CA9 | |
| SCHEMBL9812947 | 0.85 | TBXA2R (0.65) | TBXA2RTBXAS1CA12CA1CA2 | |
| SCHEMBL11335798 | 0.85 | TBXA2R (0.76) | TBXA2RTBXAS1KEAP1CA12CA1 | |
| SCHEMBL9813009 | 0.84 | TBXA2R (0.63) | TBXA2RTBXAS1CA12CA1CA2 | |
| SCHEMBL5725662 | 0.84 | PPARA (0.54) | FFAR1CA12CA1CA2CA4 | |
| SCHEMBL4662858 | 0.81 | CYP19A1 (0.74) | KEAP1CYP19A1MAPTALDH1A1 | |
| SCHEMBL21048461 | 0.80 | KEAP1 (0.81) | KEAP1CA12CA1CA2CA9 | |
| SCHEMBL9617068 | 0.79 | SGMS1 (0.63) | TBXA2RTBXAS1LMNAALDH1A1SGMS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223593-B1 | PHENOXYALKYLCARBOXYLIC ACIDS AND ESTERS AND THEIR PREPARATION AND PHARMACEUTICAL FORMULATION | GLAXO GROUP LIMITED (GB) | 1991-08-07 | — | — | EP | disclosed |
| EP-0223593-A2 | Phenoxyalkylcarboxylic acids and esters and their preparation and pharmaceutical formulation | GLAXO GROUP LIMITED (GB) | 1987-05-27 | — | — | EP | disclosed |