SCHEMBL9812995

SCHEMBL9812995

O=C(Cl)c1cc(C(=O)Cl)c(Cl)cc1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
CASP1 P29466 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ALDH1A1 P00352 6/20 0.40
KDM4E B2RXH2 1/20 0.40
MAPT P10636 1/20 0.40
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA3 P07451 2/20 0.39
CA4 P22748 2/20 0.39
CA6 P23280 2/20 0.39
CA5A P35218 2/20 0.39
CA7 P43166 2/20 0.39
CA9 Q16790 2/20 0.39
CA13 Q8N1Q1 2/20 0.39
CA14 Q9ULX7 2/20 0.39
CA5B Q9Y2D0 2/20 0.39
CISD1 Q9NZ45 1/20 0.39
ALOX15 P16050 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1312984 0.92 TSHR (0.39) TSHRCASP1SMN1; SMN2ALDH1A1KDM4E
SCHEMBL101268 0.91 TSHR (0.42) TSHRCASP1SMN1; SMN2ALDH1A1KDM4E
SCHEMBL1180396 0.83 ALDH1A1 (0.45) TSHRSMN1; SMN2ALDH1A1MAPTALOX15
SCHEMBL10630611 0.83 CD44 (0.39) TSHRCASP1SMN1; SMN2ALDH1A1KDM4E
SCHEMBL338945 0.81 ALDH1A1 (0.43) TSHRCASP1SMN1; SMN2ALDH1A1KDM4E
SCHEMBL3820327 0.79 POLB (0.53) TSHRSMN1; SMN2ALDH1A1MAPTALOX15
SCHEMBL10630827 0.79 SMN1; SMN2 (0.35) TSHRCASP1SMN1; SMN2ALDH1A1KDM4E
SCHEMBL29098888 0.79 GAA (0.43) TSHRCASP1SMN1; SMN2ALDH1A1KDM4E
SCHEMBL7656107 0.79 ALDH1A1 (0.42) TSHRCASP1SMN1; SMN2ALDH1A1KDM4E
SCHEMBL10974982 0.78 NPC1 (0.48) TSHRSMN1; SMN2ALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0113252-B1 PROCESS FOR PRODUCING BLOCK COPOLYAMIDE TORAY INDUSTRIES, INC. (JP) 1991-08-07 EP disclosed
US-4507465-A IMPACT STRENGTH TORAY INDUSTRIES, INC. (JP) 1985-03-26 US disclosed
EP-0113252-A2 Process for producing block copolyamide TORAY INDUSTRIES, INC. (JP) 1984-07-11 EP disclosed
US-4039502-A DOPES, SULFURIC ACID, FLUOROSULFONIC ACID E. I. DU PONT DE NEMOURS & COMPANY (US) 1977-08-02 US disclosed
US-3966656-A FIBER AND FILM FORMING E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-06-29 US disclosed