SCHEMBL338945

SCHEMBL338945

O=C(Cl)c1cc(C(=O)Cl)c(C(=O)Cl)cc1C(=O)Cl

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.43
ALOX15 P16050 1/20 0.43
MAOB P27338 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
TSHR P16473 2/20 0.31
TP53 P04637 1/20 0.31
CASP1 P29466 1/20 0.31
DAO P14920 1/20 0.31
TPMT P51580 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11316478 0.87 ALDH1A1 (0.41) ALDH1A1ALOX15SMN1; SMN2KDM4ETSHR
SCHEMBL7047489 0.87 ALDH1A1 (0.41) ALDH1A1ALOX15SMN1; SMN2KDM4ETSHR
SCHEMBL11703883 0.87 ALDH1A1 (0.41) ALDH1A1ALOX15SMN1; SMN2KDM4ETSHR
SCHEMBL11704719 0.87 ALDH1A1 (0.41) ALDH1A1ALOX15SMN1; SMN2KDM4ETSHR
SCHEMBL895353 0.87 ALDH1A1 (0.41) ALDH1A1ALOX15SMN1; SMN2KDM4ETSHR
SCHEMBL9860412 0.83 MAOB (0.39) ALDH1A1ALOX15MAOBMAPT
SCHEMBL7656107 0.83 ALDH1A1 (0.42) ALDH1A1ALOX15MAOBSMN1; SMN2KDM4E
SCHEMBL9812995 0.81 TSHR (0.41) ALDH1A1ALOX15MAOBSMN1; SMN2KDM4E
SCHEMBL28525271 0.81 ALDH1A1 (0.54) ALDH1A1ALOX15SMN1; SMN2MAPTTSHR
SCHEMBL2265112 0.81 ALOX15 (0.37) ALDH1A1ALOX15MAOBSMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1084 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117654312-B Preparation method and device of expanded polytetrafluoroethylene tube membrane and application of preparation method and device ZHEJIANG SCI-TECH UNIVERSITY (CN) 2026-05-26 CN claimed
US-12616948-B2 Polyamide microcapsules FIRMENICH SA (CH) 2026-05-05 US claimed
US-20250302760-A1 BIODEGRADABLE, CONTROLLED RELEASE MICROCAPSULES ENCAPSYS, LLC (US) 2025-10-02 US claimed
CN-119931028-A Novel aramid polymer 烯驰科技河北有限公司 2025-05-06 CN claimed
CN-119425424-A Polyamide composite membrane based on nanobubble-assisted free interface polymerization strategy and preparation method and application thereof 中国海洋大学 2025-02-14 CN claimed
WO-2024250573-A1 REVERSE OSMOSIS MEMBRANE PREPARATION METHOD AND REVERSE OSMOSIS MEMBRANE PREPARED THEREBY 沃顿科技股份有限公司 2024-12-12 WO claimed
CN-118949689-A Amphoteric ion modified fluorine-containing poly (ester) amide thin layer composite reverse osmosis membrane, and preparation method and application thereof 天津工业大学绍兴柯桥研究院 2024-11-15 CN claimed
US-20240375074-A9 POLYAMIDE MICROCAPSULES FIRMENICH & CIE (CH) 2024-11-14 US claimed
CN-118892750-A Preparation method of environment-friendly functional molecule-mediated ammonia nitrogen interception type ultrathin polyamide reverse osmosis membrane 哈尔滨工业大学 2024-11-05 CN claimed
US-12121868-B2 Doubly porous multi-layer desal membrane KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-10-22 US claimed
WO-2020127743-A1 POLYAMIDE MICROCAPSULES FIRMENICH SA (CH) 2020-06-25 WO claimed
US-9889413-B2 Polyetherimide composite nanofiltration membrane and preparation method thereof TIANJIN UNIVERSITY (CN) 2018-02-13 US claimed
US-20170157574-A1 POLYETHERIMIDE COMPOSITE NANOFILTRATION MEMBRANE AND PREPARATION METHOD THEREOF TIANJIN UNIVERSITY (CN) 2017-06-08 US claimed
US-20120255898-A1 SEMIPERMEABLE POLYMERS AND METHOD FOR PRODUCING SAME ELTRON RESEARCH & DEVELOPMENT, INC. (US) 2012-10-11 US claimed
WO-2010042250-A2 SEMIPERMEABLE POLYMERS AND METHOD FOR PRODUCING SAME ELTRON RESEARCH AND DEVELOPMENT, INC. (US) 2010-04-15 WO claimed
US-20100006495-A1 SEMIPERMEABLE POLYMERS AND METHOD FOR PRODUCING SAME ELTRON RESEARCH AND DEVELOPMENT, INC. (US) 2010-01-14 US claimed
EP-1149836-B1 Polynalbuphine derivatives HU OLIVER YOA PU (TW) 2003-02-26 EP claimed
EP-0198202-B1 NOVEL N-CYCLOHEXYL-POLYCARBOXAMIDE COMPOUND AND DERIVATIVES THEREOF, PROCESSES FOR PREPARING THEM, AND USE OF THEM IN PREPARATION OF HOST-GUEST COMPLEXES MITSUBISHI CORPORATION (JP) 1991-07-17 EP claimed
EP-0198202-A2 Novel N-cyclohexyl-polycarboxamide compound and derivatives thereof, processes for preparing them, and use of them in preparation of host-guest complexes MITSUBISHI CORPORATION (JP) 1986-10-22 EP claimed
US-4582893-A Aromatic polyesters which contain terminal or lateral radicals with two conjugated double bonds BAYER AKTIENGESELLSCHAFT (DE) 1986-04-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12616948-B2 Polyamide microcapsules HDHD5, DDC, USP39 ALDH1A1 4007/4885ALOX15 3255/4885MAOB 3395/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.