Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7929417 | 0.91 | ALDH1A1 (0.45) | ALDH1A1ALOX15POLBAPEX1HPGD | |
| SCHEMBL3820327 | 0.88 | POLB (0.53) | ALDH1A1ALOX15POLBAPEX1HPGD | |
| SCHEMBL9793665 | 0.86 | ALDH1A1 (0.45) | ALDH1A1ALOX15POLBAPEX1HPGD | |
| SCHEMBL9812995 | 0.83 | TSHR (0.41) | ALDH1A1ALOX15HPGDTSHRMAPT | |
| SCHEMBL30180915 | 0.82 | ALDH1A1 (0.45) | ALDH1A1ALOX15POLBAPEX1HPGD | |
| SCHEMBL8508742 | 0.82 | POLB (0.43) | ALDH1A1POLBAPEX1HPGDTSHR | |
| SCHEMBL221449 | 0.82 | KEAP1 (0.53) | ALDH1A1POLBAPEX1HPGDTSHR | |
| SCHEMBL2366229 | 0.81 | KDM1A (0.43) | ALDH1A1ALOX15POLBAPEX1HPGD | |
| SCHEMBL1312984 | 0.80 | TSHR (0.39) | ALDH1A1ALOX15POLBHPGDTSHR | |
| SCHEMBL23272826 | 0.80 | CA12 (0.53) | ALDH1A1POLBAPEX1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 348 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119874514-A | Synthesis method of fluoroquinolone drug intermediate | 帕潘纳(北京)科技有限公司 | 2025-04-25 | — | — | CN | claimed |
| CN-118324627-A | Method for preparing 2, 4-dichloro-5-fluorobenzoyl chloride | 东南大学 | 2024-07-12 | — | — | CN | claimed |
| CN-116462631-A | Synthetic method of norfloxacin | 青海夏都医药有限公司 | 2023-07-21 | — | — | CN | claimed |
| CN-109734581-B | Preparation method of fluoroquinolone intermediate 2, 4-dichloro-5-fluorobenzoyl chloride | 和鼎（南京）医药技术有限公司 | 2022-04-05 | — | — | CN | claimed |
| CN-111269131-B | Process for preparing cyclopropyl ethyl amide by taking tri-n-propylamine as acid acceptor | 江苏飞宇医药科技股份有限公司 | 2021-12-28 | — | — | CN | claimed |
| CN-214973946-U | Device for realizing continuous water washing in production process of 2, 4-dichloro-5-fluorobenzoyl chloride | 江苏飞宇医药科技股份有限公司 | 2021-12-03 | — | — | CN | claimed |
| CN-109553524-B | Synthetic method of 2, 4-dichloro-5-fluorobenzoyl chloride | 浙江本立科技股份有限公司 | 2021-11-09 | — | — | CN | claimed |
| CN-214159605-U | Residual liquid neutralizing kettle for producing 2, 4-dichloro-5-fluorobenzoyl chloride | 江苏飞宇医药科技股份有限公司 | 2021-09-10 | — | — | CN | claimed |
| CN-214166030-U | Fluorobenzene metering tank for producing 2, 4-dichloro-5-fluorobenzoyl chloride | 江苏飞宇医药科技股份有限公司 | 2021-09-10 | — | — | CN | claimed |
| CN-112979456-A | Method for recycling rectification residual liquid in production process of 2, 4-dichloro-5-fluorobenzoyl chloride | 常州飞宇化工有限公司 | 2021-06-18 | — | — | CN | claimed |
| US-5859298-A | REACTING 2,4-DICHLORO-5-FLUORO-BENZOYL CHLORIDE WITH POTASSIUM FLUORIDE IN AN APROTIC SOLVENT; DISTILLATION | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-12 | — | — | US | claimed |
| EP-0673912-B1 | Process for preparing 2-halogeno-4,5-difluoro-benzofluorides | BAYER AG (DE) | 1998-12-23 | — | — | EP | claimed |
| US-5565614-A | FLUORINATION | BAYER AKTIENGESELLSCHAFT (DE) | 1996-10-15 | — | — | US | claimed |
| EP-0583705-A1 | Process for the preparation of 2,3,4-trichloro-5-fluoro-benzoylchloride | BAYER AG (DE) | 1994-02-23 | — | — | EP | claimed |
| EP-0354444-B1 | PROCESS FOR THE INTRODUCTION OF FLUORINE ON AROMATIC NUCLEUS BY NUCLEOPHILIC EXCHANGE | BAYER AG (DE) | 1993-01-20 | — | — | EP | claimed |
| EP-0354444-A2 | Process for the introduction of fluorine on aromatic nucleus by nucleophilic exchange | BAYER AG (DE) | 1990-02-14 | — | — | EP | claimed |
| EP-0176846-B1 | 3-AMINO-2-BENZOYL-ACRYLIC-ACID DERIVATIVES AND PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1989-08-16 | — | — | EP | claimed |
| EP-0164619-B1 | 2,4,5-TRIHALO OR 2,3,4,5-TETRAHALO BENZENE DERIVATIVES AND PROCESS FOR PRODUCING THEM | BAYER AG (DE) | 1988-10-12 | — | — | EP | claimed |
| EP-0176846-A2 | 3-Amino-2-benzoyl-acrylic-acid derivatives and process for their preparation | BAYER AG (DE) | 1986-04-09 | — | — | EP | claimed |
| US-4439620-A | CHEMICAL INTERMEDIATE | BAYER AKTIENGESELLSCHAFT (DE) | 1984-03-27 | — | — | US | claimed |