⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1636193 | 0.81 | ALDH1A1 (0.30) | — | |
| SCHEMBL641833 | 0.75 | TP53 (0.31) | — | |
| SCHEMBL10935255 | 0.73 | — | — | |
| SCHEMBL8765564 | 0.72 | HDAC3 (0.37) | — | |
| SCHEMBL16243043 | 0.72 | LTA4H (0.36) | — | |
| SCHEMBL19466456 | 0.71 | CES1 (0.34) | — | |
| SCHEMBL9192214 | 0.71 | — | — | |
| SCHEMBL630589 | 0.70 | TP53 (0.33) | — | |
| SCHEMBL928063 | 0.70 | TSHR (0.33) | — | |
| SCHEMBL28241337 | 0.70 | LOXL2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240262970-A1 | METHOD FOR IMPROVING THE ADHESION OF SILICONE ELASTOMERS TO PRE-CURED SILICONE ELASTOMERIC SUBSTRATES, AND PRIMER COMPOSITION FOR SILICONE RUBBER COMPOSITIONS AND ELASTOMERIC MATERIALS | DOW SILICONES CORPORATION | 2024-08-08 | — | — | US | disclosed |
| US-20220204770-A1 | PRIMER FOR SILICONE RUBBER COMPOSITIONS AND ELASTOMERIC MATERIALS | DOW SILICONES CORPORATION | 2022-06-30 | — | — | US | disclosed |
| CN-113677769-A | Primer for silicone rubber composition and elastomer material | 美国陶氏有机硅公司 | 2021-11-19 | — | — | CN | disclosed |
| WO-2020223182-A1 | PRIMER FOR SILICONE RUBBER COMPOSITIONS AND ELASTOMERIC MATERIALS | DOW SILICONES CORPORATION (US) | 2020-11-05 | — | — | WO | disclosed |
| EP-0207634-B1 | BONDING PRIMER COMPOSITION | Toray Silicone Company, Ltd. (JP) | 1991-08-07 | — | — | EP | disclosed |
| US-4681636-A | T-BUTYLPEROXYSILANE, DI- OR POLYALKOXY SILICON COMPOUND, ORGANOTITANATE ESTER, SOLVENT | TORAY SILICONE CO., LTD. (JP) | 1987-07-21 | — | — | US | disclosed |
| EP-0207634-A2 | Bonding primer composition | Toray Silicone Company, Ltd. (JP) | 1987-01-07 | — | — | EP | disclosed |
| EP-0092003-B1 | FOAM CONTROL COMPOSITIONS | Toray Silicone Co., Ltd. (JP) | 1986-03-05 | — | — | EP | disclosed |
| EP-0064375-B1 | ROOM TEMPERATURE CURABLE POLYORGANOSILOXANE COMPOSITION CONTAINING SPINDLE SHAPED CALCIUM CARBONATE | Toray Silicone Company Limited (JP) | 1986-01-22 | — | — | EP | disclosed |
| US-4534815-A | Adhesive primer composition and bonding method employing same | TORAY SILICONE CO., LTD. (JP) | 1985-08-13 | — | — | US | disclosed |
| EP-0061871-B1 | PRIMER COMPOSITION USED FOR ADHESION OF SILICONE RUBBER AND APPLICATION METHOD | Toray Silicone Company Limited (JP) | 1984-10-31 | — | — | EP | disclosed |
| US-4454262-A | USING A PARTICULATE CARBONATE SALT | TORAY SILICONE COMPANY, LTD. (JP) | 1984-06-12 | — | — | US | disclosed |
| US-4443359-A | POLYSILOXANES, SILICA, NITROGEN CONTAINING SILICON COMPOUNDS | TORAY SILICONE COMPANY, LTD. (JP) | 1984-04-17 | — | — | US | disclosed |
| EP-0051363-B1 | AN ADHESIVE PRIMER COMPOSITION | Toray Silicone Co., Ltd. (JP) | 1984-04-04 | — | — | EP | disclosed |
| EP-0092003-A1 | Foam control compositions | Toray Silicone Co., Ltd. (JP) | 1983-10-26 | — | — | EP | disclosed |
| US-4401500-A | SILICONE RUBBERS, ALKOXYSILANE, HYDROPEROXIDE | DOW CORNING CORPORATION (US) | 1983-08-30 | — | — | US | disclosed |
| EP-0061871-A1 | Primer composition used for adhesion of silicone rubber and application method | Toray Silicone Company Limited (JP) | 1982-10-06 | — | — | EP | disclosed |
| EP-0051363-A1 | An adhesive primer composition | Toray Silicone Co., Ltd. (JP) | 1982-05-12 | — | — | EP | disclosed |