SCHEMBL928063

SCHEMBL928063

OC[SiH](O[SiH3])c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
ALDH1A1 P00352 1/20 0.32
RECQL P46063 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
LTA4H P09960 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL630589 0.77 TP53 (0.33) LTA4H
SCHEMBL28241337 0.77 LOXL2 (0.33)
SCHEMBL641833 0.74 TP53 (0.31) LTA4H
SCHEMBL252065 0.72 ALDH1A1 (0.30) TSHRALDH1A1
SCHEMBL9419498 0.72 TSHR (0.30) TSHR
SCHEMBL1636193 0.72 ALDH1A1 (0.30) TSHRALDH1A1
SCHEMBL8765564 0.71 HDAC3 (0.37)
SCHEMBL16243043 0.71 LTA4H (0.36) TSHRTDP1LTA4H
SCHEMBL9813028 0.70
SCHEMBL9618285 0.69 TDP1 (0.42) TSHRALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109026836-B Fan, manufacturing method thereof, fan assembly and electric appliance 广东美的厨房电器制造有限公司 2021-01-26 CN disclosed
EP-1750657-B1 SHINY FOUNDATION NOXELL CORP (US) 2018-09-05 EP disclosed
EP-1602352-B1 Cosmetic foundation comprising cross-linked, non-emulsifying organopolysiloxane elastomer PROCTER & GAMBLE (US) 2013-03-06 EP disclosed
US-8017136-B2 Shiny foundation THE PROCTER & GAMBLE COMPANY (US) 2011-09-13 US disclosed
US-7892570-B2 Cosmetic foundation THE PROCTER & GAMBLE COMPANY (US) 2011-02-22 US disclosed
US-7867505-B2 Foundation THE PROCTER & GAMBLE COMPANY (US) 2011-01-11 US disclosed
US-20060263310-A1 metal oxide particles; and cross-linked organopolysiloxane elastomer,wherein organo-functionalised silicone fibrils are bonded to and extend away from the surface of the metal oxide particles; provide steric stabilisation; sun screen agents; cosmetics NOXELL CORPORATION 2006-11-23 US disclosed
EP-1709953-A1 Composition comprising metal oxides THE PROCTER & GAMBLE COMPANY (US) 2006-10-11 EP disclosed
US-20060222610-A1 Composition comprising metal oxides PROCTER & GAMBLE COMPANY, THE 2006-10-05 US disclosed
US-20050281770-A1 Shiny foundation DEUTSCHE BANK TRUST COMPANY AMERICAS, AS COLLATERAL AGENT 2005-12-22 US disclosed
EP-1602352-A1 Cosmetic foundation comprising cross-linked, non-emulsifying organopolysiloxane elastomer THE PROCTER & GAMBLE COMPANY (US) 2005-12-07 EP disclosed
EP-1600145-A1 Foundation comprising cross-linked organopolysiloxane elastomer The Procter & Gamble Company (US) 2005-11-30 EP disclosed
US-20050260149-A1 Cosmetic foundation DEUTSCHE BANK TRUST COMPANY AMERICAS, AS COLLATERAL AGENT 2005-11-24 US disclosed
US-4034140-A Heat-curable silicone elastomers having unprimed adhesion DOW CORNING CORPORATION (US) 1977-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050281770-A1 Shiny foundation CCNY, ZYX, LOXL3 TSHR 1104/4885ALDH1A1 2480/4885RECQL 625/4885
US-20050260149-A1 Cosmetic foundation CUTA, PLOD3, LPO TSHR 1987/4885ALDH1A1 2001/4885RECQL 694/4885
US-20060263310-A1 metal oxide particles; and cross-linked organopolysiloxane elastomer,wherein organo-functionalised silicone fibrils are bonded to and extend away from the surface of the metal oxide particles; provide steric stabilisation; sun screen agents; cosmetics PLOD3, MAN2B1, PLOD2 TSHR 1625/4885ALDH1A1 2574/4885RECQL 521/4885
US-20060222610-A1 Composition comprising metal oxides CD68, MACO1, ITGA1 TSHR 3094/4885ALDH1A1 4220/4885RECQL 2845/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.