Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 3/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813058 | 1.00 | SIGMAR1 (0.53) | SIGMAR1ALDH1A1KDM4ECHRM2CHRM4 | |
| SCHEMBL3920722 | 0.82 | ALDH1A1 (0.51) | SIGMAR1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11375264 | 0.81 | ALDH1A1 (0.64) | SIGMAR1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL1930719 | 0.80 | ALDH1A1 (0.50) | SIGMAR1ALDH1A1KDM4ECHRM2CHRM1 | |
| SCHEMBL9346869 | 0.79 | ALDH1A1 (0.60) | SIGMAR1ALDH1A1KDM4ECHRM2CHRM4 | |
| SCHEMBL6537026 | 0.79 | MAPT (0.56) | SIGMAR1ALDH1A1KDM4ELMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL11272257 | 0.78 | KMT2A (0.50) | SIGMAR1ALDH1A1CHRM2CHRM4CHRM5 | |
| SCHEMBL21896503 | 0.78 | KDM4E (0.67) | SIGMAR1ALDH1A1KDM4ECHRM2CHRM4 | |
| SCHEMBL9813060 | 0.77 | KMT2A (0.45) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL17335821 | 0.74 | ALDH1A1 (0.50) | SIGMAR1ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266549-B1 | CINNAMYL AMINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1991-06-19 | — | — | EP | claimed |
| EP-0266549-A1 | Cinnamyl amines, process for their preparation and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1988-05-11 | — | — | EP | claimed |
| EP-0266549-B1 | CINNAMYL AMINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1991-06-19 | — | — | EP | disclosed |
| EP-0266549-A1 | Cinnamyl amines, process for their preparation and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1988-05-11 | — | — | EP | disclosed |