Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3920722 | 0.82 | ALDH1A1 (0.51) | KMT2AMEN1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL1930719 | 0.80 | ALDH1A1 (0.50) | KMT2AMEN1ALDH1A1MAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11272257 | 0.78 | KMT2A (0.50) | KMT2AMEN1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL9813058 | 0.77 | SIGMAR1 (0.53) | KMT2AMEN1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL9813063 | 0.77 | SIGMAR1 (0.53) | KMT2AMEN1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL41501 | 0.69 | SIGMAR1 (0.71) | KMT2ALMNA | |
| SCHEMBL15577550 | 0.68 | FKBP1A (0.42) | KMT2AMEN1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL7352120 | 0.67 | GAA (0.65) | KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL6619692 | 0.67 | ALDH1A1 (0.63) | KMT2AMEN1ALDH1A1MAPK1MAPT | |
| SCHEMBL662989 | 0.67 | SLC6A3 (0.68) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266549-B1 | CINNAMYL AMINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1991-06-19 | — | — | EP | claimed |
| EP-0266549-A1 | Cinnamyl amines, process for their preparation and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1988-05-11 | — | — | EP | claimed |
| EP-0266549-B1 | CINNAMYL AMINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1991-06-19 | — | — | EP | disclosed |
| EP-0266549-A1 | Cinnamyl amines, process for their preparation and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1988-05-11 | — | — | EP | disclosed |