Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.53 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.53 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.53 |
| ▸ | DNM2 | P50570 | 10/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813342 | 0.75 | CHRNB2 (0.49) | CHRNB2CHRNB4CHRNA3CHRNA4CNR1 | |
| SCHEMBL10896792 | 0.72 | MAPT (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4DNM2 | |
| SCHEMBL28521075 | 0.72 | MAPT (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4DNM2 | |
| SCHEMBL9243403 | 0.72 | MAPT (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4DNM2 | |
| SCHEMBL9813328 | 0.70 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL15402675 | 0.69 | KCNH3 (0.53) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL8073238 | 0.68 | SLC29A1 (0.43) | CHRNB2CHRNB4CHRNA3CHRNA4TLR8 | |
| SCHEMBL11667177 | 0.67 | NR5A1 (0.56) | — | |
| SCHEMBL9813368 | 0.67 | CHRNB2 (0.43) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL17537570 | 0.67 | ADH1B (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434576-A1 | Thermotropic adducts from non-mesogenic species bound by hydrogen bonds and method for their preparation | RHONE-POULENC CHIMIE (FR) | 1991-06-26 | — | — | EP | disclosed |