SCHEMBL9813634

SCHEMBL9813634

CNC(=O)Oc1cccc2c1CC=CC2

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.51
ALDH1A1 P00352 4/20 0.50
PGR P06401 1/20 0.50
GAA P10253 1/20 0.50
PTGS1 P23219 1/20 0.50
MAPK1 P28482 1/20 0.50
HSD17B10 Q99714 1/20 0.50
ACHE P22303 8/20 0.46
BCHE P06276 4/20 0.44
KDM4E B2RXH2 1/20 0.40
KMT2A Q03164 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CHRM2 P08172 1/20 0.37
CHRM1 P11229 1/20 0.37
CHRM3 P20309 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.35
LIPE Q05469 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10454754 0.82 MAPK1 (0.44) LMNAALDH1A1GAAPTGS1MAPK1
SCHEMBL1872704 0.78 LMNA (0.51) LMNAALDH1A1PGRGAAPTGS1
SCHEMBL11711658 0.77 LMNA (0.50) LMNAALDH1A1PGRGAAPTGS1
SCHEMBL31245777 0.76 ALDH1A1 (0.51) LMNAALDH1A1PGRGAAPTGS1
SCHEMBL506157 0.72 DRD2 (0.46) ACHECHRM2CHRM1CHRM3
SCHEMBL9813616 0.72 LMNA (0.48) LMNAALDH1A1PGRGAAPTGS1
SCHEMBL11114382 0.71 LMNA (0.56) LMNAALDH1A1PGRGAAPTGS1
SCHEMBL11725965 0.69 ALDH1A1 (0.61) LMNAALDH1A1PGRGAAPTGS1
SCHEMBL30989358 0.68 ALDH1A1 (0.57) LMNAALDH1A1PGRGAAPTGS1
SCHEMBL5191682 0.68 ALDH1A1 (0.57) LMNAALDH1A1PGRGAAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0178908-B1 CO-EXTRUSION OF MULTI-COMPONENT ECTOPARASITICIDAL PET COLLARS CONAGRA PET PRODUCTS, INC. (US) 1991-07-31 EP disclosed
US-4803956-A Animal collar for controlling fleas and ticks A. H. ROBINS COMPANY, INCORPORATED (US) 1989-02-14 US disclosed
EP-0178908-A2 Co-extrusion of multi-component ectoparasiticidal pet collars CONAGRA PET PRODUCTS, INC. (US) 1986-04-23 EP disclosed
US-4332817-A CARBAMATES WITH ALKANEDIOLS CELANESE CORPORATION (US) 1982-06-01 US disclosed
US-4226881-A ARYL OR HETEROCYCLIC N-ALKYL CARBAMATE, SYNERGISTIC ALKANEDIOL CELANESE CORPORATION (US) 1980-10-07 US disclosed
US-4150109-A DIAZINON, DIAZOXONE, COLLARS DICK PIERRE R G 1979-04-17 US disclosed