SCHEMBL9813644

SCHEMBL9813644

CC1CC(C)(C)NC(C)(C)C1.O=C(O)N1CCCC1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
HSD11B1 P28845 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
GAA P10253 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
LMNA P02545 2/20 0.33
POLB P06746 1/20 0.32
BIRC2 Q13490 1/20 0.32
BPTF Q12830 1/20 0.32
HPGD P15428 2/20 0.31
EZH2 Q15910 1/20 0.31
MAPK1 P28482 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9813606 0.98 HSD11B1 (0.36) MEN1KMT2AHSD11B1L3MBTL1GAA
Acetic Acid SCHEMBL9813575 0.78 GAA (0.41) KMT2AL3MBTL1GAAPOLBEZH2
Cyclohexane SCHEMBL9813599 0.77 GAA (0.38) KMT2AGAALMNAPOLBEZH2
SCHEMBL3592259 0.75 MAPK1 (0.44) MEN1KMT2AGAALMNAPOLB
SCHEMBL327787 0.73 RECQL (0.38) MEN1KMT2AL3MBTL1GAALMNA
Acrylic Acid SCHEMBL9813704 0.72 LMNA (0.40) KMT2AGAALMNAPOLBEZH2
Methacrylic Acid SCHEMBL9813684 0.72 GAA (0.37) KMT2AGAAPOLBEZH2ALDH1A1
SCHEMBL9813699 0.71 APLNR (0.41) HSD11B1GAASMN1; SMN2LMNAPOLB
SCHEMBL2994350 0.71 RECQL (0.37) MEN1KMT2AL3MBTL1GAALMNA
SCHEMBL76824 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0163245-B1 DERIVATIVES OF ALKYL-SUBSTITUTED 4-HYDROXY-METHYL-PIPERIDINE AND USE THEREOF AS STABILIZERS AUSIMONT S.r.l. (IT) 1991-07-31 EP disclosed
US-4772708-A STABILIZERS FOR POLYMERS AUSIMONT S.P.A. (IT) 1988-09-20 US disclosed
EP-0163245-A2 Derivatives of alkyl-substituted 4-hydroxy-methyl-piperidine and use thereof as stabilizers AUSIMONT S.r.l. (IT) 1985-12-04 EP disclosed