SCHEMBL9813709

SCHEMBL9813709

CC1CC(C)(C)NC(C)(C)C1.Cc1cccc(C(=O)O)c1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.46
HSD17B10 Q99714 3/20 0.41
KDM4E B2RXH2 3/20 0.41
ALDH1A1 P00352 3/20 0.41
HPGD P15428 2/20 0.41
KMT2A Q03164 3/20 0.40
CCR2 P41597 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
GAA P10253 2/20 0.40
MYC P01106 1/20 0.39
MEN1 O00255 1/20 0.38
MAPT P10636 1/20 0.38
GFER P55789 1/20 0.38
POLB P06746 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
EZH2 Q15910 2/20 0.36
METAP2 P50579 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL80110 0.78 ALDH1A1 (0.63) ALOX15HSD17B10KDM4EALDH1A1HPGD
SCHEMBL29400205 0.78 ALDH1A1 (0.63) ALOX15HSD17B10KDM4EALDH1A1HPGD
Naphthoic Acid SCHEMBL9813601 0.78 KMT2A (0.62) ALOX15KDM4EALDH1A1HPGDKMT2A
Pyromellitic Acid SCHEMBL9813658 0.77 ALOX15 (0.46) ALOX15HSD17B10KDM4EKMT2ACCR2
Pyromellitic Acid SCHEMBL10684063 0.77 ALOX15 (0.46) ALOX15HSD17B10KDM4EKMT2ACCR2
SCHEMBL28519356 0.77 ALDH1A1 (0.61) ALOX15HSD17B10KDM4EALDH1A1HPGD
Methane SCHEMBL27599096 0.77 ALDH1A1 (0.61) ALOX15HSD17B10KDM4EALDH1A1HPGD
SCHEMBL14831124 0.77 ALDH1A1 (0.61) ALOX15HSD17B10KDM4EALDH1A1HPGD
Hydrochloric Acid SCHEMBL7258725 0.77 ALDH1A1 (0.61) ALOX15HSD17B10KDM4EALDH1A1HPGD
Hydrochloric Acid SCHEMBL301551 0.77 ALDH1A1 (0.61) ALOX15HSD17B10KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0163245-B1 DERIVATIVES OF ALKYL-SUBSTITUTED 4-HYDROXY-METHYL-PIPERIDINE AND USE THEREOF AS STABILIZERS AUSIMONT S.r.l. (IT) 1991-07-31 EP disclosed
US-4772708-A STABILIZERS FOR POLYMERS AUSIMONT S.P.A. (IT) 1988-09-20 US disclosed
EP-0163245-A2 Derivatives of alkyl-substituted 4-hydroxy-methyl-piperidine and use thereof as stabilizers AUSIMONT S.r.l. (IT) 1985-12-04 EP disclosed