Pyromellitic Acid

Pyromellitic Acid

SCHEMBL9813658

CC1CC(C)(C)NC(C)(C)C1.O=C(O)c1cc(C(=O)O)c(C(=O)O)cc1C(=O)O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.46
GAA P10253 1/20 0.41
POLB P06746 2/20 0.41
HSD17B10 Q99714 1/20 0.40
EZH2 Q15910 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.37
ATM Q13315 1/20 0.37
HTT P42858 1/20 0.37
GLA P06280 1/20 0.37
CCR2 P41597 1/20 0.36
KMT2A Q03164 4/20 0.36
MEN1 O00255 2/20 0.36
KDM4E B2RXH2 1/20 0.36
PKM P14618 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyromellitic Acid SCHEMBL10684063 1.00 ALOX15 (0.46) ALOX15GAAPOLBHSD17B10EZH2
SCHEMBL9813697 0.86 ALOX15 (0.45) ALOX15GAAPOLBHSD17B10EZH2
SCHEMBL10681714 0.86 ALOX15 (0.45) ALOX15GAAPOLBHSD17B10EZH2
SCHEMBL10679973 0.85 GAA (0.45) ALOX15GAAPOLBHSD17B10EZH2
Salicylic Acid SCHEMBL9813624 0.80 ALDH1A1 (0.55) ALOX15GAAPOLBHSD17B10EZH2
Acetic Acid SCHEMBL9813575 0.80 GAA (0.41) ALOX15GAAPOLBEZH2L3MBTL1
Benzoic Acid SCHEMBL9813692 0.79 GAA (0.58) ALOX15GAAPOLBEZH2L3MBTL1
SCHEMBL9813709 0.77 ALOX15 (0.46) ALOX15GAAPOLBHSD17B10EZH2
Naphthoic Acid SCHEMBL9813601 0.77 KMT2A (0.62) ALOX15GAAPOLBEZH2L3MBTL1
Pyromellitic Acid SCHEMBL9813687 0.76 CCR2 (0.36) GAAHTTCCR2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0163245-B1 DERIVATIVES OF ALKYL-SUBSTITUTED 4-HYDROXY-METHYL-PIPERIDINE AND USE THEREOF AS STABILIZERS AUSIMONT S.r.l. (IT) 1991-07-31 EP disclosed
EP-0163245-A2 Derivatives of alkyl-substituted 4-hydroxy-methyl-piperidine and use thereof as stabilizers AUSIMONT S.r.l. (IT) 1985-12-04 EP disclosed