Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.53 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.44 |
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SCN4A | P35499 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | PNLIP | P16233 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | BAX | Q07812 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11402358 | 0.86 | GSTP1 (0.56) | GSTP1BCAT2PARP10FFAR4MCL1 | |
| SCHEMBL18825620 | 0.83 | BCAT2 (0.59) | BCAT2SLC6A4SLC6A3GAA | |
| SCHEMBL229441 | 0.83 | BCAT2 (0.63) | BCAT2SLC6A4SLC6A3GAA | |
| SCHEMBL4131227 | 0.83 | GAA (0.57) | SLC6A4SLC6A3HSP90AA1HSP90AB1POLB | |
| SCHEMBL9532086 | 0.81 | BCAT2 (0.55) | BCAT2SLC6A4SLC6A3GAA | |
| SCHEMBL9222322 | 0.80 | GSTP1 (0.59) | GSTP1SLC6A3PARP10FFAR4MCL1 | |
| SCHEMBL6793681 | 0.79 | SERPINE1 (0.47) | SLC6A4SLC6A3FFAR4DHODH | |
| SCHEMBL9243804 | 0.79 | CTNNB1 (0.62) | PARP10SRD5A2GAA | |
| SCHEMBL29697586 | 0.78 | BCAT2 (0.47) | BCAT2SLC6A4SLC6A3GAA | |
| SCHEMBL28640320 | 0.78 | SLC6A3 (0.64) | BCAT2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0225144-B1 | COPOLYETHERKETONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-08-07 | — | — | EP | disclosed |
| EP-0229470-B1 | BRANCHED COPOLYETHERKETONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-01-30 | — | — | EP | disclosed |
| US-4720537-A | Branched copolyetherketones | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-01-19 | — | — | US | disclosed |
| US-4704448-A | MOLDING MATERIALS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-11-03 | — | — | US | disclosed |
| EP-0229470-A1 | Branched copolyetherketones | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-07-22 | — | — | EP | disclosed |
| EP-0225144-A2 | Copolyetherketones | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-06-10 | — | — | EP | disclosed |