Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 3/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9368212 | 0.79 | ALDH1A1 (0.40) | ALDH1A1POLBTDP1L3MBTL1MAOB | |
| SCHEMBL9814427 | 0.79 | GAA (0.46) | KIF11ALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL7522786 | 0.76 | ALDH1A1 (0.41) | KIF11ALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL10666026 | 0.76 | MAOB (0.55) | KIF11ALDH1A1TDP1APPMAOB | |
| SCHEMBL29689723 | 0.76 | MAOB (0.55) | KIF11ALDH1A1TDP1APPMAOB | |
| SCHEMBL9814448 | 0.72 | KDM4E (0.34) | ALDH1A1POLBTDP1L3MBTL1MEN1 | |
| SCHEMBL4184980 | 0.72 | KIF11 (0.50) | KIF11ALDH1A1HSD17B3APPMAOB | |
| SCHEMBL24445659 | 0.70 | KDM4E (0.50) | KIF11ALDH1A1HSD17B3TDP1KDM4E | |
| SCHEMBL1029516 | 0.70 | CAMK2A (0.50) | KIF11AR | |
| SCHEMBL10357217 | 0.69 | KIF11 (0.40) | KIF11ALDH1A1HSD17B3APPLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251013-B1 | FLUORINE CONTAINING O-AMINOPHENOLS | BAYER AG (DE) | 1991-08-21 | — | — | EP | disclosed |
| EP-0251013-A2 | Fluorine containing o-aminophenols | BAYER AG (DE) | 1988-01-07 | — | — | EP | disclosed |