Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.44 |
| ▸ | TYR | P14679 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3022860 | 0.82 | KIF11 (0.52) | KIF11HSD17B1TYRALDH1A1NR1I2 | |
| SCHEMBL30368360 | 0.82 | KIF11 (0.52) | KIF11HSD17B1TYRALDH1A1NR1I2 | |
| SCHEMBL5511642 | 0.80 | ALDH1A1 (0.60) | KIF11HSD17B1TYRALDH1A1NR1I2 | |
| SCHEMBL30595362 | 0.80 | ALDH1A1 (0.60) | KIF11HSD17B1TYRALDH1A1NR1I2 | |
| SCHEMBL2506023 | 0.79 | KCNJ11 (0.47) | KIF11TYRALDH1A1NR1I2LMNA | |
| SCHEMBL2001354 | 0.78 | CES2 (0.55) | KIF11ALDH1A1CYP2C9ALOX15HSD17B10 | |
| SCHEMBL29427775 | 0.78 | CA3 (0.52) | KIF11HSD17B1ARCES2CA9 | |
| SCHEMBL187345 | 0.78 | KIF11 (0.70) | KIF11HSD17B3APPAR | |
| SCHEMBL4343525 | 0.78 | CA3 (0.52) | KIF11HSD17B1ARCES2CA9 | |
| SCHEMBL29689656 | 0.78 | KIF11 (0.70) | KIF11HSD17B3APPAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101302163-A | Preparation of 2,4-bis (2,6-binitro-4-trifluoromethyl phenoxy) benzotrifluoride | UNIV DONGHUA (CN) | 2008-11-12 | — | — | CN | claimed |
| US-20210171883-A1 | ANTIVIRAL WIPER | FUJIFILM CORPORATION (JP) | 2021-06-10 | — | — | US | disclosed |
| US-9914719-B2 | Hydroxybenzamide derivatives and their use as inhibitors of HSP90 | ASTEX THERAPEUTICS LTD. (GB) | 2018-03-13 | — | — | US | disclosed |
| US-9730912-B2 | Pharmaceutical compounds | ASTEX THERAPEUTICS LIMITED (GB) | 2017-08-15 | — | — | US | disclosed |
| US-20090192152-A1 | Novel Antigiardial Agents and Methods of Use Thereof | UNIVERSITY OF MISSISSIPPI | 2009-07-30 | — | — | US | disclosed |
| US-7468445-B2 | Antigiardial agents and use thereof | UNIVERSITY OF MISSISSIPPI (US) | 2008-12-23 | — | — | US | disclosed |
| CN-101302163-A | Preparation of 2,4-bis (2,6-binitro-4-trifluoromethyl phenoxy) benzotrifluoride | UNIV DONGHUA (CN) | 2008-11-12 | — | — | CN | disclosed |
| CN-101302163-A | Preparation of 2,4-bis (2,6-binitro-4-trifluoromethyl phenoxy) benzotrifluoride | UNIV DONGHUA (CN) | 2008-11-12 | — | — | CN | disclosed |
| US-7208559-B2 | Ethylened polymer and molded object obtained therefrom | MITSUI CHEMICALS, INC. (JP) | 2007-04-24 | — | — | US | disclosed |
| US-20060135712-A1 | Ethylened polymer and molded object obtained therefrom | MITSUI CHEMICALS, INC. (JP) | 2006-06-22 | — | — | US | disclosed |
| US-20060106091-A1 | Antigiardial agents and use thereof | THE UNIVERSITY OF MISSISSIPPI | 2006-05-18 | — | — | US | disclosed |
| WO-2004014886-A1 | ANTIGIARDIAL AGENTS AND USE THEREOF | UNIVERSITY OF MISSISSIPPI (US) | 2004-02-19 | — | — | WO | disclosed |
| US-4731450-A | Process for perfluoroalkylation of aromatic derivatives | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1988-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106091-A1 | Antigiardial agents and use thereof | GPER1, ENPP2, ALPI | KIF11 2340/4885HSD17B1 1438/4885TYR 3219/4885 |
| US-20090192152-A1 | Novel Antigiardial Agents and Methods of Use Thereof | ENPP2, GPER1, ALPI | KIF11 2521/4885HSD17B1 1282/4885TYR 3268/4885 |
| US-20210171883-A1 | ANTIVIRAL WIPER | CGAS, PRKX, PDE4C | KIF11 3061/4885HSD17B1 2323/4885TYR 3222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.