Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9814482 | 0.91 | TSHR (0.47) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL8849031 | 0.89 | ALDH1A1 (0.48) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL9814484 | 0.87 | THRB (0.45) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL15798306 | 0.84 | ALDH1A1 (0.53) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL9814478 | 0.81 | THRB (0.43) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL19259269 | 0.80 | ALDH1A1 (0.41) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL2033070 | 0.78 | ALDH1A1 (0.48) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL891719 | 0.78 | ALDH1A1 (0.48) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL18495622 | 0.76 | TSHR (0.50) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL29524745 | 0.76 | LMNA (0.58) | TSHRALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0290883-B1 | MODIFIED DIENE POLYMER RUBBERS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-09-18 | — | — | EP | disclosed |
| US-4885338-A | REACTING ALKALI METAL-CONTAINING CONJUGATED DIENE POLYMER WITH NITROALKYL ACRYLATE OR NITROAMINO COMPOUND; TIRE TREADS, IMPACT RESILIENCE, REDUCED HARDNESS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-12-05 | — | — | US | disclosed |