Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 7/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CPA1 | P15085 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15798306 | 0.91 | ALDH1A1 (0.53) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL9814484 | 0.91 | THRB (0.45) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL9814468 | 0.89 | TSHR (0.42) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL19259269 | 0.87 | ALDH1A1 (0.41) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL9814482 | 0.86 | TSHR (0.47) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL2033070 | 0.85 | ALDH1A1 (0.48) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL891719 | 0.85 | ALDH1A1 (0.48) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL6421553 | 0.81 | ALDH1A1 (0.52) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL8849877 | 0.81 | ALDH1A1 (0.52) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL15799604 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TP53HIF1ACYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2931768-B1 | NITROFUNCTIONAL ACRYLATE COPOLYMERS FOR BINDER COMPOSITIONS | ANGUS CHEMICAL (US) | 2017-08-16 | — | — | EP | claimed |
| JP-2127411-A | — | — | None | — | — | JP | disclosed |
| EP-2931768-B1 | NITROFUNCTIONAL ACRYLATE COPOLYMERS FOR BINDER COMPOSITIONS | ANGUS CHEMICAL (US) | 2017-08-16 | — | — | EP | disclosed |
| US-9676957-B2 | Nitrofunctional acrylate copolymers for binder compositions | ANGUS CHEMICAL COMPANY (US) | 2017-06-13 | — | — | US | disclosed |
| US-9676957-B2 | Nitrofunctional acrylate copolymers for binder compositions | ANGUS CHEMICAL COMPANY (US) | 2017-06-13 | — | — | US | disclosed |
| US-9670134-B2 | Synthesis of (2-nitro)alkyl (meth)acrylates via transesterification of (meth)acrylate esters | ANGUS CHEMICAL COMPANY (US) | 2017-06-06 | — | — | US | disclosed |
| US-9670134-B2 | Synthesis of (2-nitro)alkyl (meth)acrylates via transesterification of (meth)acrylate esters | ANGUS CHEMICAL COMPANY (US) | 2017-06-06 | — | — | US | disclosed |
| US-20160046558-A1 | SYNTHESIS OF (2-NITRO)ALKYL (METH)ACRYLATES VIA TRANSESTERIFICATION OF (METH)ACRYLATE ESTERS | ADVANCION CORPORATION | 2016-02-18 | — | — | US | disclosed |
| US-20160046558-A1 | SYNTHESIS OF (2-NITRO)ALKYL (METH)ACRYLATES VIA TRANSESTERIFICATION OF (METH)ACRYLATE ESTERS | ADVANCION CORPORATION | 2016-02-18 | — | — | US | disclosed |
| US-20150322281-A1 | NITROFUNCTIONAL ACRYLATE COPOLYMERS FOR BINDER COMPOSITIONS | ADVANCION CORPORATION | 2015-11-12 | — | — | US | disclosed |
| US-20150322281-A1 | NITROFUNCTIONAL ACRYLATE COPOLYMERS FOR BINDER COMPOSITIONS | ADVANCION CORPORATION | 2015-11-12 | — | — | US | disclosed |
| WO-2014158445-A1 | SYNTHESIS OF (2-NITRO)ALKYL (METH)ACRYLATES VIA TRANSESTERIFICATION OF (METH)ACRYLATE ESTERS | ROHM AND HAAS COMPANY (US) | 2014-10-02 | — | — | WO | disclosed |
| WO-2014092914-A1 | NITROFUNCTIONAL ACRYLATE COPOLYMERS FOR BINDER COMPOSITIONS | ANGUS CHEMICAL COMPANY (US) | 2014-06-19 | — | — | WO | disclosed |
| EP-0412606-B1 | UV-stabilization of polymers using nitro compounds | AKZO NOBEL NV (NL) | 1997-01-15 | — | — | EP | disclosed |
| EP-0355900-B1 | Grafting of hindered C-nitro compounds onto polymers | AKZO NOBEL NV (NL) | 1994-05-18 | — | — | EP | disclosed |
| US-5122555-A | Mixing with polyolefin and conventional stabilizer | AKZO NV (NL) | 1992-06-16 | — | — | US | disclosed |
| US-5098957-A | Polymers for prosthetics for implants | AKZO NV (NL) | 1992-03-24 | — | — | US | disclosed |
| EP-0412606-A1 | UV-stabilization of polymers using nitro compounds | Akzo Nobel N.V. (NL) | 1991-02-13 | — | — | EP | disclosed |
| JP-H02127411-A | METHOD FOR GRAFTING HINDERED C-NITRO COMPOUND ONTO PERFORMED POLYMER | AKZO NV | 1990-05-16 | — | — | JP | disclosed |
| EP-0355900-A1 | Grafting of hindered C-nitro compounds onto polymers | Akzo Nobel N.V. (NL) | 1990-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160046558-A1 | SYNTHESIS OF (2-NITRO)ALKYL (METH)ACRYLATES VIA TRANSESTERIFICATION OF (METH)ACRYLATE ESTERS | NAT1, NOS2, NOS1 | ALDH1A1 43/4885TP53 3078/4885HIF1A 3077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.