Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALPG | P10696 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2188570 | 0.76 | NPC1 (0.39) | ALDH1A1LMNASMN1; SMN2EPHX1DRD2 | |
| SCHEMBL9199931 | 0.75 | TSHR (0.39) | ALDH1A1HPGDNR3C2SRD5A2MEN1 | |
| SCHEMBL6562734 | 0.70 | MAOB (0.33) | EPHX1ATM | |
| Benzene SCHEMBL27709388 | 0.69 | ALDH1A1 (0.70) | ALDH1A1LMNAHPGDSMN1; SMN2NPSR1 | |
| SCHEMBL7940606 | 0.69 | ALDH1A1 (0.70) | ALDH1A1LMNAHPGDSMN1; SMN2NPSR1 | |
| SCHEMBL17068941 | 0.69 | ALDH1A1 (0.70) | ALDH1A1LMNAHPGDSMN1; SMN2NPSR1 | |
| SCHEMBL27483853 | 0.69 | ALDH1A1 (0.70) | ALDH1A1LMNAHPGDSMN1; SMN2NPSR1 | |
| SCHEMBL251921 | 0.69 | ALDH1A1 (0.70) | ALDH1A1LMNAHPGDSMN1; SMN2NPSR1 | |
| SCHEMBL7373156 | 0.67 | ALDH1A1 (0.67) | ALDH1A1LMNAHPGDSMN1; SMN2NPSR1 | |
| SCHEMBL238259 | 0.65 | LTA4H (0.73) | ALDH1A1LMNAHPGDSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262919-B1 | PREPARATION OF ARYL CARBONYL COMPOUNDS | RAYCHEM LIMITED (GB) | 1991-09-11 | — | — | EP | disclosed |
| US-4898983-A | FRIEDEL-CRAFTS PROCESS; LEWIS ACIDS, BY-PRODUCT INHIBITION; ACID HALIDES, ACTIVE HYDROGEN AROMATIC COMPONENTS; CONTROLLING AGENTS | RAYCHEM LIMITED (GB) | 1990-02-06 | — | — | US | disclosed |
| EP-0262919-A2 | Preparation of aryl carbonyl compounds | RAYCHEM LIMITED (GB) | 1988-04-06 | — | — | EP | disclosed |