Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | BAD | Q92934 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10505742 | 0.85 | CES2 (0.43) | MAPTCES2CES1MEN1KMT2A | |
| SCHEMBL1119643 | 0.77 | THRB (0.35) | EPHX1POLBTDP1 | |
| SCHEMBL9814883 | 0.76 | ALDH1A1 (0.38) | NPC1RAB9AATMEPHX1DRD2 | |
| SCHEMBL5320069 | 0.71 | LMNA (0.37) | ATMEPHX1MAPTCES2CES1 | |
| SCHEMBL10533324 | 0.71 | CES2 (0.44) | NPC1RAB9AMAPTCES2CES1 | |
| SCHEMBL9851147 | 0.71 | NPC1 (0.37) | NPC1RAB9AATMEPHX1DRD2 | |
| SCHEMBL8463882 | 0.70 | CES1 (0.48) | NPC1RAB9AATMMAPTCES2 | |
| SCHEMBL8970777 | 0.70 | MAPT (0.43) | ATMMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL746904 | 0.69 | HTR2A (0.38) | — | |
| SCHEMBL222998 | 0.68 | CHRNA7 (0.35) | MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342261-A1 | IMPROVED METHOD FOR THE MANUFACTURE OF POLY(ARYL ETHER KETONE)S AND IMPROVED METHOD FOR PROVIDING A SODIUM CARBONATE SUITABLE FOR THE MANUFACTURE OF POLY(ARYL ETHER KETONE)S | Solvay Advanced Polymers, L.L.C. (US) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010046487-A1 | IMPROVED METHOD FOR THE MANUFACTURE OF POLY(ARYL ETHER KETONE)S AND IMPROVED METHOD FOR PROVIDING A SODIUM CARBONATE SUITABLE FOR THE MANUFACTURE OF POLY(ARYL ETHER KETONE)S | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2010-04-29 | — | — | WO | disclosed |