Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | TDO2 | P48775 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28228155 | 0.77 | HSD17B10 (0.59) | IMPDH2HSD17B10MAPK1MAPTMEN1 | |
| SCHEMBL28399449 | 0.76 | MEN1 (0.65) | IMPDH2HSD17B10MAPK1MAPTMEN1 | |
| SCHEMBL15903807 | 0.74 | TDO2 (0.56) | IMPDH2HSD17B10MAPK1MAPTMEN1 | |
| SCHEMBL1202543 | 0.73 | IMPDH2 (0.63) | IMPDH2HSD17B10MAPK1MAPTMEN1 | |
| SCHEMBL1563156 | 0.72 | HSD17B10 (0.50) | IMPDH2HSD17B10MAPK1MAPTMEN1 | |
| SCHEMBL20017674 | 0.72 | PDGFRB (0.65) | IMPDH2HSD17B10MAPK1MAPTMEN1 | |
| SCHEMBL2929592 | 0.72 | IMPDH2 (0.46) | IMPDH2HSD17B10MAPK1MAPTMEN1 | |
| SCHEMBL27695699 | 0.71 | CLK1 (0.53) | IMPDH2HSD17B10MAPK1MAPTMEN1 | |
| SCHEMBL16481896 | 0.71 | IGF1R (0.49) | IMPDH2HSD17B10MAPK1MAPTMEN1 | |
| SCHEMBL6422966 | 0.70 | KDM4E (0.47) | HSD17B10MAPK1MAPTTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214238-B | Preparation and application of indole oxadiazole derivative with acylated piperazine structure | 济南大学 | 2022-07-22 | — | — | CN | claimed |
| CN-113200971-B | Synthesis and application of indole oxadiazole derivative with aryl piperazine structure | 济南大学 | 2022-06-28 | — | — | CN | claimed |
| CN-113214238-A | Preparation and application of indole oxadiazole derivative with acylated piperazine structure | 济南大学 | 2021-08-06 | — | — | CN | claimed |
| CN-113200971-A | Synthesis and application of indole oxadiazole derivative with aromatic piperazine structure | 济南大学 | 2021-08-03 | — | — | CN | claimed |
| CN-113214238-B | Preparation and application of indole oxadiazole derivative with acylated piperazine structure | 济南大学 | 2022-07-22 | — | — | CN | disclosed |
| CN-113214238-B | Preparation and application of indole oxadiazole derivative with acylated piperazine structure | 济南大学 | 2022-07-22 | — | — | CN | disclosed |
| CN-113200971-B | Synthesis and application of indole oxadiazole derivative with aryl piperazine structure | 济南大学 | 2022-06-28 | — | — | CN | disclosed |
| CN-113200971-B | Synthesis and application of indole oxadiazole derivative with aryl piperazine structure | 济南大学 | 2022-06-28 | — | — | CN | disclosed |
| CN-113214238-A | Preparation and application of indole oxadiazole derivative with acylated piperazine structure | 济南大学 | 2021-08-06 | — | — | CN | disclosed |
| CN-113214238-A | Preparation and application of indole oxadiazole derivative with acylated piperazine structure | 济南大学 | 2021-08-06 | — | — | CN | disclosed |
| CN-113200971-A | Synthesis and application of indole oxadiazole derivative with aromatic piperazine structure | 济南大学 | 2021-08-03 | — | — | CN | disclosed |
| CN-113200971-A | Synthesis and application of indole oxadiazole derivative with aromatic piperazine structure | 济南大学 | 2021-08-03 | — | — | CN | disclosed |
| WO-2007084413-A2 | METHODS FOR TREATING HEPATITIS C | PTC THERAPEUTICS, INC. (US) | 2007-07-26 | — | — | WO | disclosed |
| EP-1771169-A1 | METHODS FOR TREATING HEPATITIS C | PTC Therapeutics, Inc. (US) | 2007-04-11 | — | — | EP | disclosed |
| US-20060223863-A1 | Methods for treating Hepatitis C | KARP GARY M | 2006-10-05 | — | — | US | disclosed |
| US-20060189606-A1 | Methods for treating hepatitis C | PTC THERAPEUTICS, INC. | 2006-08-24 | — | — | US | disclosed |
| WO-2006019831-A1 | METHODS FOR TREATING HEPATITIS C | PTC THERAPEUTICS, INC. (US) | 2006-02-23 | — | — | WO | disclosed |
| US-6930104-B2 | Heterocyclic derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-08-16 | — | — | US | disclosed |
| US-20040157850-A1 | Novel heterocyclic derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-08-12 | — | — | US | disclosed |
| EP-1382598-A1 | NOVEL HETEROCYCLIC DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2004-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157850-A1 | Novel heterocyclic derivatives | APP, BACE1, PSEN1 | IMPDH2 4821/4885HSD17B10 1602/4885MAPK1 382/4885 |
| US-20060189606-A1 | Methods for treating hepatitis C | HAVCR2, EIF2AK2, MAVS | IMPDH2 812/4885HSD17B10 1276/4885MAPK1 4248/4885 |
| US-20060223863-A1 | Methods for treating Hepatitis C | OAT, HAVCR2, HCCS | IMPDH2 477/4885HSD17B10 886/4885MAPK1 4384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.