Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 10/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9815065 | 0.87 | MEN1 (0.42) | TLR8KCNH2MEN1KMT2ACYP3A4 | |
| SCHEMBL1024836 | 0.86 | CYP3A4 (0.43) | TLR8KCNH2MEN1KMT2ACYP3A4 | |
| SCHEMBL11689404 | 0.86 | CYP1A2 (0.38) | MEN1KMT2ACYP3A4TSHRTDP1 | |
| SCHEMBL27949370 | 0.84 | GHSR (0.33) | TLR8MEN1KMT2ACYP3A4TSHR | |
| SCHEMBL11692367 | 0.81 | HPGD (0.44) | TLR8MEN1KMT2ACYP3A4TSHR | |
| Pyrene SCHEMBL4416467 | 0.80 | MEN1 (0.45) | TLR8KCNH2MEN1KMT2ACYP3A4 | |
| SCHEMBL3747524 | 0.80 | MEN1 (0.45) | TLR8KCNH2MEN1KMT2ACYP3A4 | |
| SCHEMBL10436263 | 0.80 | KCNH2 (0.38) | TLR8KCNH2MEN1KMT2ACYP3A4 | |
| SCHEMBL11131281 | 0.79 | HSD17B10 (0.47) | TLR8KCNH2MEN1KMT2ACYP3A4 | |
| SCHEMBL2177583 | 0.79 | MEN1 (0.39) | TLR8KCNH2MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447949-A1 | Optical oxygen sensor | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-25 | — | — | EP | claimed |
| EP-0381026-A2 | Optical oxygen sensor | F. HOFFMANN-LA ROCHE AG (CH) | 1990-08-08 | — | — | EP | claimed |
| EP-0447949-A1 | Optical oxygen sensor | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-25 | — | — | EP | disclosed |
| EP-0381026-A2 | Optical oxygen sensor | F. HOFFMANN-LA ROCHE AG (CH) | 1990-08-08 | — | — | EP | disclosed |