Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1024836 | 0.98 | CYP3A4 (0.43) | MEN1KMT2ACYP3A4TSHRTDP1 | |
| SCHEMBL11692367 | 0.94 | HPGD (0.44) | MEN1KMT2ACYP3A4TSHRTDP1 | |
| SCHEMBL2177583 | 0.90 | MEN1 (0.39) | MEN1KMT2ACYP3A4TSHRTDP1 | |
| SCHEMBL9815019 | 0.87 | TLR8 (0.39) | MEN1KMT2ACYP3A4TSHRTDP1 | |
| SCHEMBL3747524 | 0.86 | MEN1 (0.45) | MEN1KMT2ACYP3A4TSHRTDP1 | |
| Pyrene SCHEMBL4416467 | 0.86 | MEN1 (0.45) | MEN1KMT2ACYP3A4TSHRTDP1 | |
| SCHEMBL11690814 | 0.84 | CYP1A2 (0.44) | MEN1KMT2ACYP3A4TSHRTDP1 | |
| SCHEMBL8225761 | 0.84 | MEN1 (0.46) | MEN1KMT2ACYP3A4TSHRTDP1 | |
| SCHEMBL5746968 | 0.84 | ALDH1A1 (0.41) | CYP3A4TSHRTDP1ALDH1A1HPGD | |
| SCHEMBL5749154 | 0.84 | TLR8 (0.47) | MEN1KMT2ACYP3A4ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447949-A1 | Optical oxygen sensor | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-25 | — | — | EP | claimed |
| EP-0381026-A2 | Optical oxygen sensor | F. HOFFMANN-LA ROCHE AG (CH) | 1990-08-08 | — | — | EP | claimed |
| EP-0447949-A1 | Optical oxygen sensor | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-25 | — | — | EP | disclosed |
| EP-0381026-A2 | Optical oxygen sensor | F. HOFFMANN-LA ROCHE AG (CH) | 1990-08-08 | — | — | EP | disclosed |