SCHEMBL9815155

SCHEMBL9815155

COc1cccc(C(=O)O)c1S(=O)(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.53
CA12 O43570 2/20 0.52
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA7 P43166 2/20 0.52
CA9 Q16790 2/20 0.52
CA14 Q9ULX7 2/20 0.52
ALOX15 P16050 1/20 0.50
KDM4E B2RXH2 6/20 0.47
HPGD P15428 6/20 0.47
ALDH1A1 P00352 5/20 0.47
HSD17B10 Q99714 3/20 0.47
KMT2A Q03164 2/20 0.46
FABP4 P15090 2/20 0.46
FABP3 P05413 1/20 0.46
FABP5 Q01469 1/20 0.46
MAPK1 P28482 1/20 0.44
TSHR P16473 2/20 0.43
ESR1 P03372 1/20 0.43
ITGB3 P05106 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6357865 0.86 HTT (0.53) HTTCA12CA1CA2CA7
SCHEMBL18762909 0.85 CA12 (0.42) HTTCA12CA1CA2CA7
SCHEMBL1734479 0.84 MAPT (0.57) HTTALOX15KDM4EHPGDALDH1A1
SCHEMBL8361898 0.83 STS (0.50) HTTALOX15ALDH1A1HSD17B10KMT2A
SCHEMBL669064 0.83 CA2 (0.48) HTTCA12CA1CA2CA7
Dimethylamine SCHEMBL7018332 0.82 GAA (0.47) CA1CA2CA9KDM4EHPGD
SCHEMBL27462851 0.82 HMGCR (0.45) HTTCA12CA1CA2CA7
SCHEMBL65889 0.81 ALOX15 (0.59) CA12CA1CA2CA7CA9
Benzene SCHEMBL10638262 0.81 ALOX15 (0.59) CA12CA1CA2CA7CA9
SCHEMBL18762908 0.81 SLC6A3 (0.46) HTTCA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0227931-B1 A METHOD FOR PRODUCING CYCLOALKANOLS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-09-11 EP claimed
US-4691064-A CATALYST OF AROMATIC SULFONIC ACID HAVING AT LEAST ONE HYDROXYL OR ETHER GROUP SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-09-01 US claimed
EP-0227931-A2 A method for producing cycloalkanols SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-07-08 EP claimed
US-4691064-A CATALYST OF AROMATIC SULFONIC ACID HAVING AT LEAST ONE HYDROXYL OR ETHER GROUP SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-09-01 US disclosed