SCHEMBL9815437

SCHEMBL9815437

ClCC(Cl)CCc1ccc(Cl)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.46
MAOB P27338 1/20 0.41
SLC6A4 P31645 1/20 0.40
AOC3 Q16853 1/20 0.39
IDO1 P14902 1/20 0.39
HTR3E A5X5Y0 1/20 0.38
HTR3B O95264 1/20 0.38
HTR3A P46098 1/20 0.38
HTR3D Q70Z44 1/20 0.38
HTR3C Q8WXA8 1/20 0.38
MIF P14174 1/20 0.38
KCNH2 Q12809 1/20 0.38
TMEM97 Q5BJF2 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A3 Q01959 1/20 0.38
IGF1R P08069 1/20 0.37
ALOX15 P16050 1/20 0.37
DAO P14920 1/20 0.37
PPARG P37231 2/20 0.37
PPARA Q07869 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6605635 0.80 TSHR (0.43) TAAR1KCNH2ALOX15
SCHEMBL409924 0.77 TAAR1 (0.45) TAAR1MAOBIDO1HTR3EHTR3B
SCHEMBL28210143 0.76 TAAR1 (0.48) TAAR1MAOBSLC6A4AOC3IDO1
SCHEMBL6465824 0.75 MMP12 (0.46) PPARGPPARA
SCHEMBL9492547 0.74 PPARG (0.51) TAAR1DAOPPARGPPARA
SCHEMBL6823686 0.73 TAAR1 (0.56) TAAR1MAOBSLC6A4AOC3IDO1
SCHEMBL11062642 0.73 TAAR1 (0.50) TAAR1MAOBSLC6A4AOC3IDO1
SCHEMBL436099 0.73 AOC3 (0.52) TAAR1MAOBSLC6A4AOC3IDO1
SCHEMBL7956101 0.73 TAAR1 (0.56) TAAR1MAOBSLC6A4AOC3IDO1
SCHEMBL2135113 0.72 TAAR1 (0.68) TAAR1MAOBSLC6A4AOC3IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0336216-B1 PROCESS FOR THE PREPARATION OF MONOCARBOXYLIC ACID ANHYDRIDES HOECHST AKTIENGESELLSCHAFT (DE) 1991-12-27 EP disclosed
EP-0332969-B1 PROCESS FOR THE PREPARATION OF MONOCARBOXYLIC-ACID ANHYDRIDES HOECHST AKTIENGESELLSCHAFT (DE) 1991-10-09 EP disclosed
EP-0336215-B1 SUPPORTED CATALYST FOR THE PREPARATION OF ANHYDRIDES OF MONOCARBOXYLIC ACIDS HOECHST AKTIENGESELLSCHAFT (DE) 1991-05-15 EP disclosed
US-4965234-A Supported catalyst for the preparation of monocarboxylic anhydrides HOECHST AKTIENGESELLSCHAFT (DE) 1990-10-23 US disclosed
US-4959498-A Process for the preparation of monocarboxylic anhydrides HOECHST AKTIENGESELLSCHAFT (DE) 1990-09-25 US disclosed
US-4952727-A Process for the preparation of monocarboxylic anhydrides HOECHST AKTIENGESELLSCHAFT (DE) 1990-08-28 US disclosed
EP-0336215-A1 Supported catalyst for the preparation of anhydrides of monocarboxylic acids HOECHST AKTIENGESELLSCHAFT (DE) 1989-10-11 EP disclosed
EP-0336216-A1 Process for the preparation of monocarboxylic acid anhydrides HOECHST AKTIENGESELLSCHAFT (DE) 1989-10-11 EP disclosed
EP-0332970-A1 Supported catalyst for monocarboxylic acid anhydrides preparation HOECHST AKTIENGESELLSCHAFT (DE) 1989-09-20 EP disclosed
EP-0332969-A1 Process for the preparation of monocarboxylic-acid anhydrides HOECHST AKTIENGESELLSCHAFT (DE) 1989-09-20 EP disclosed