Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | NPY1R | P25929 | 1/20 | 0.65 |
| ▸ | NPY2R | P49146 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 6/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.47 |
| ▸ | PDE2A | O00408 | 2/20 | 0.47 |
| ▸ | PDE1A | P54750 | 1/20 | 0.47 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.47 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 3/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.45 |
| ▸ | RARB | P10826 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21969533 | 0.88 | MAPT (0.63) | LMNANPY1RNPY2RMAPTSMN1; SMN2 | |
| SCHEMBL8100411 | 0.86 | SMN1; SMN2 (0.53) | LMNANPY1RNPY2RMAPTSMN1; SMN2 | |
| SCHEMBL8100532 | 0.86 | SMN1; SMN2 (0.53) | LMNANPY1RNPY2RMAPTSMN1; SMN2 | |
| SCHEMBL8110737 | 0.84 | SMN1; SMN2 (0.54) | LMNANPY1RNPY2RMAPTSMN1; SMN2 | |
| SCHEMBL8114164 | 0.83 | SMN1; SMN2 (0.55) | LMNANPY1RNPY2RMAPTSMN1; SMN2 | |
| SCHEMBL7297347 | 0.80 | SMN1; SMN2 (0.58) | LMNANPY1RNPY2RMAPTSMN1; SMN2 | |
| SCHEMBL7358963 | 0.80 | SMN1; SMN2 (0.58) | LMNANPY1RNPY2RMAPTSMN1; SMN2 | |
| SCHEMBL10967326 | 0.79 | LMNA (1.00) | LMNANPY1RNPY2RMAPTSMN1; SMN2 | |
| SCHEMBL10474199 | 0.78 | LMNA (0.62) | LMNANPY1RNPY2RMAPTSMN1; SMN2 | |
| SCHEMBL10353452 | 0.78 | SMN1; SMN2 (0.81) | LMNANPY1RNPY2RMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0160416-B1 | SUBSTITUTED PYRIDAZINES | Chisso Corporation (JP) | 1991-09-11 | — | — | EP | disclosed |
| US-4657695-A | FERROELECTRIC LIQUIDS CRYSTALS | CHISSO CORPORATION (JP) | 1987-04-14 | — | — | US | disclosed |
| EP-0160416-A2 | Substituted pyridazines | Chisso Corporation (JP) | 1985-11-06 | — | — | EP | disclosed |