⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4394008 | 0.88 | — | — | |
| SCHEMBL3977545 | 0.82 | — | — | |
| SCHEMBL4738398 | 0.80 | SIGMAR1 (0.39) | — | |
| SCHEMBL6907900 | 0.79 | — | — | |
| SCHEMBL27075809 | 0.75 | — | — | |
| SCHEMBL7160776 | 0.75 | — | — | |
| SCHEMBL21987120 | 0.73 | ALDH1A1 (0.38) | — | |
| SCHEMBL94099 | 0.73 | — | — | |
| SCHEMBL2462839 | 0.73 | ALDH1A1 (0.32) | — | |
| SCHEMBL4396289 | 0.73 | SIGMAR1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732896-B1 | SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | AVENTIS PHARMA INC (US) | 2012-12-12 | — | — | EP | claimed |
| US-20120202795-A1 | SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | AVENTIS PHARMACEUTICALS INC. (US) | 2012-08-09 | — | — | US | claimed |
| US-7462613-B2 | Pyridazinone derivatives as pharmaceuticals and pharmaceutical compositions containing them | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-12-09 | — | — | US | claimed |
| US-20070032489-A1 | SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | AVENTIS PHARMACEUTICALS INC. (US) | 2007-02-08 | — | — | US | claimed |
| EP-1732896-A1 | SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | Aventis Pharmaceuticals Inc. (US) | 2006-12-20 | — | — | EP | claimed |
| WO-2005097750-A1 | SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | AVENTIS PHARMACEUTICALS INC. (US) | 2005-10-20 | — | — | WO | claimed |
| EP-0355597-B1 | SUBSTITUTED DIOXOLANYLETHYLAMINES, PROCESS FOR THEIR PREPARATION, THEIR USE IN PESTICIDES, AND INTERMEDIATES | BAYER AG (DE) | 1993-06-09 | — | — | EP | claimed |
| US-4985421-A | Fungicidal substituted dioxolanylethylamine | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-15 | — | — | US | claimed |
| EP-0355597-A1 | Substituted dioxolanylethylamines, process for their preparation, their use in pesticides, and intermediates | BAYER AG (DE) | 1990-02-28 | — | — | EP | claimed |
| JP-6145245-A | — | — | None | — | — | JP | disclosed |
| JP-6145166-A | — | — | None | — | — | JP | disclosed |
| CN-122029163-A | Chemical for targeting chromatin remodeling complexes and uses thereof | 丹娜-法伯癌症研究院 | 2026-05-12 | — | — | CN | disclosed |
| WO-2025075967-A1 | CHEMICAL MATTERS FOR TARGETING CHROMATIN REMODELING COMPLEXES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2025-04-10 | — | — | WO | disclosed |
| US-20190209483-A1 | METHOD OF ENHANCING THE BIODISTRIBUTION AND TISSUE TARGETING PROPERTIES OF THERAPEUTIC CECO2 PARTICLES VIA NANO-ENCAPSULATION AND COATING | PEROXYIUM INC (US) | 2019-07-11 | — | — | US | disclosed |
| US-4681893-A | Trans-6-[2-(3- or 4-carboxamido-substituted pyrrol-1-yl)alkyl]-4-hydroxypyran-2-one inhibitors of cholesterol synthesis | WARNER-LAMBERT COMPANY (US) | 1987-07-21 | — | — | US | disclosed |
| US-4647576-A | Trans-6-[2-(substitutedpyrrol-1-yl)alkyl]-pyran-2-one inhibitors of cholesterol synthesis | WARNER-LAMBERT COMPANY (US) | 1987-03-03 | — | — | US | disclosed |
| EP-0179559-A2 | Trans-6-[2-(substitutedpyrrol-1-yl)alkyl]-pyran-2-one inhibitors of cholesterol synthesis | WARNER-LAMBERT COMPANY (US) | 1986-04-30 | — | — | EP | disclosed |
| US-4529435-A | Controlling weed growth | PPG INDUSTRIES, INC. (US) | 1985-07-16 | — | — | US | disclosed |
| US-4255182-A | PRE- AND POSTEMERGENCE HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1981-03-10 | — | — | US | disclosed |
| US-4057560-A | 1,2,2A,3,4,5 Hexahydrobenz[c,d]indol-1-yl-2-guanidines | SANDOZ LTD. (CH) | 1977-11-08 | — | — | US | disclosed |